ArticleScientific reports2018
The Arabidopsis RNA Polymerase II Carboxyl Terminal Domain (CTD) Phosphatase-Like1 (CPL1) is a biotic stress susceptibility gene.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- RNA-binding proteins orchestrating immunity in plants.The Plant journal : for cell and molecular biology · 2025Review
- C-TERMINAL DOMAIN PHOSPHATASE-LIKE 1 promotes flowering with TAF15b by repressing the floral repressor gene FLOWERING LOCUS C.Molecules and cells · 2024Article
- Identification and Functional Analysis ofInternational journal of molecular sciences · 2024Article
- Genetic mechanisms underlying increased microalgal thermotolerance, maximal growth rate, and yield on light following adaptive laboratory evolution.BMC biology · 2022Article
- Transcriptional regulation of plant innate immunity.Essays in biochemistry · 2022Review
- The intersection between circadian and heat-responsive regulatory networks controls plant responses to increasing temperatures.Biochemical Society transactions · 2022Review
- Review
- C-terminal domain phosphatase-like 1 (CPL1) is involved in floral transition in Arabidopsis.BMC genomics · 2021Article
- Redox responses of Arabidopsis thaliana to the green peach aphid, Myzus persicae.Molecular plant pathology · 2021Article
- Gene co-expression network analysis of the heat-responsive core transcriptome identifies hub genes in Brassica rapa.Planta · 2021Article
- Reactive Oxygen Species in Plant Interactions With Aphids.Frontiers in plant science · 2021Review
- A Plant Stress-Responsive Bioreporter Coupled With Transcriptomic Analysis Allows Rapid Screening for Biocontrols of Necrotrophic Fungal Pathogens.Frontiers in molecular biosciences · 2021Article
- Natural Variation Uncovers Candidate Genes for Barley Spikelet Number and Grain Yield under Drought Stress.Genes · 2020Article
- The ArabidopsisPlants (Basel, Switzerland) · 2019Article
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7 authors.
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Abstract
Crop breeding for improved disease resistance may be achieved through the manipulation of host susceptibility genes. Previously we identified multiple Arabidopsis mutants known as enhanced stress response1 (esr1) that have defects in a KH-domain RNA-binding protein and conferred increased resistance to the root fungal pathogen Fusarium oxysporum. Here, screening the same mutagenized population we discovered two further enhanced stress response mutants that also conferred enhanced resistance to F. oxysporum. These mutants also have enhanced resistance to a leaf fungal pathogen (Alternaria brassicicola) and an aphid pest (Myzus persicae), but not to the bacterial leaf pathogen Pseudomonas syringae. The causal alleles in these mutants were found to have defects in the ESR1 interacting protein partner RNA Polymerase II Carboxyl Terminal Domain (CTD) Phosphatase-Like1 (CPL1) and subsequently given the allele symbols cpl1-7 and cpl1-8. These results define a new role for CPL1 as a pathogen and pest susceptibility gene. Global transcriptome analysis and oxidative stress assays showed these cpl1 mutants have increased tolerance to oxidative stress. In particular, components of biotic stress responsive pathways were enriched in cpl1 over wild-type up-regulated gene expression datasets including genes related to defence, heat shock proteins and oxidative stress/redox state processes.
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