Evidence map›Paper›PMID 30194285›Full record

ArticleThe Journal of biological chemistry2018

Oxidative cyclization of

Majd Lahham, Tea Pavkov-Keller, Michael Fuchs, Johannes Niederhauser, Gabriel Chalhoub, Bastian Daniel, Wolfgang Kroutil, Karl Gruber, Peter Macheroux

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Regioselective Biocatalytic C4-Prenylation of Unprotected Tryptophan Derivatives.Chembiochem : a European journal of chemical biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Majd LahhamFrom the Institutes of Biochemistry, Graz University of Technology, Petersgasse 12/II, 8010 Graz.
Tea Pavkov-Kellerthe Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50, 8010 Graz, and.
Michael Fuchsthe Institute of Chemistry, University of Graz, Heinrichstrasse 28/2, 8010 Graz, Austria.
Johannes NiederhauserFrom the Institutes of Biochemistry, Graz University of Technology, Petersgasse 12/II, 8010 Graz.
Gabriel ChalhoubFrom the Institutes of Biochemistry, Graz University of Technology, Petersgasse 12/II, 8010 Graz.
Bastian DanielFrom the Institutes of Biochemistry, Graz University of Technology, Petersgasse 12/II, 8010 Graz.
Wolfgang Kroutilthe Institute of Chemistry, University of Graz, Heinrichstrasse 28/2, 8010 Graz, Austria.
Karl Gruberthe Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50, 8010 Graz, and.
Peter MacherouxFrom the Institutes of Biochemistry, Graz University of Technology, Petersgasse 12/II, 8010 Graz, peter.macheroux@tugraz.at.ORCID 0000-0002-0242-454X
Graz University of Technology · ATUniversity of Graz · AT

Funding

Austrian Science Fund FWF P 31276
6 · The paper itself

Abstract

Flavin-dependent enzymes catalyze many oxidations, including formation of ring structures in natural products. The gene cluster for biosynthesis of fumisoquins, secondary metabolites structurally related to isoquinolines, in the filamentous fungus

Indexed as

Aspergillus fumigatusBinding SitesCatalytic DomainCrystallography, X-RayCyclizationDihydroxyphenylalanineFungal ProteinsKineticsMonoamine OxidaseMultigene FamilyOxidation-ReductionSubstrate SpecificityDihydroxyphenylalanineFungal ProteinsMonoamine Oxidaseamine oxidasebiosynthesisflavin adenine dinucleotide (FAD)flavoproteinfructose amine oxidasefumisoquin biosynthesisisoquinolinesoxidation-reduction (redox)oxidative cyclizationX-ray crystallography

Identifiers

PMID30194285
PMCPMC6222107
OpenAlexW2891528593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.