SynthesisThe journal of allergy and clinical immunology. In practice2019
Staphylococcus aureus Nasal Colonization and Asthma in Adults: Systematic Review and Meta-Analysis.
Synthesis in The journal of allergy and clinical immunology. In practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 76 citations in OpenAlex.
- Antimicrobial-resistant organism carriage and metagenomic characterization of the microbiome and resistome in veterinary workers.Veterinary research communications · 2026Article
- Synergistic Induction of Neutrophilic Inflammatory Programs byImmune network · 2026Article
- Comorbid Chronic Rhinosinusitis and Asthma: Shared Risk Factors and Treatment Implications-An EAACI Task Force Report.Allergy · 2026Article
- Impact of prednisolone tapering and extended dupilumab dosing intervals on comorbid asthma in patients with chronic rhinosinusitis with nasal polyps.The journal of allergy and clinical immunology. Global · 2026Article
- The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases.FEBS letters · 2025Review
- Characterisation of nasopharyngeal colonisation byBMJ open respiratory research · 2025Article
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- Repeated and alternate stimulations with dsRNA and SEB alter responses in macrophages and epithelial cells.The World Allergy Organization journal · 2025Article
- Intestinal permeability disturbances: causes, diseases and therapy.Clinical and experimental medicine · 2024Review
- Nasal Carriage, Antimicrobial Susceptibility Profile, and Enterotoxin Genes ofIndian journal of microbiology · 2024Article
- Staphylococcal enterotoxin B sensitization in eosinophilic asthma.The Korean journal of internal medicine · 2024Article
- Pre-asthma: a useful concept? A EUFOREA paper. Part 2-late onset eosinophilic asthma.Frontiers in allergy · 2024Review
- Keratinocyte-derived small extracellular vesicles supply antigens for CD1a-resticted T cells and promote their type 2 bias in the context of filaggrin insufficiency.Frontiers in immunology · 2024Article
- Association Between Nasal Colonization ofAllergy, asthma & immunology research · 2023Article
- New insights into the pathophysiology and therapeutic targets of asthma and comorbid chronic rhinosinusitis with or without nasal polyposis.Clinical science (London, England : 1979) · 2023Review
- Staphylococcal Enterotoxin-Specific IgE Sensitization: A Potential Predictor of Fixed Airflow Obstruction in Elderly Asthma.Allergy, asthma & immunology research · 2023Article
- The Role ofInternational journal of molecular sciences · 2022Review
- Compositional Alterations of the Nasal Microbiome and Staphylococcus aureus-Characterized Dysbiosis in the Nasal Mucosa of Patients With Allergic Rhinitis.Clinical and experimental otorhinolaryngology · 2022Article
- Microbiome alterations from volatile organic compounds (VOC) exposures among workers in salons primarily serving women of color.Environmental research · 2022Article
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Authors and funding
11 authors at 9 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStaphylococcus aureus (SA) is a frequent colonizer in humans, and it is known to be associated with chronic allergic diseases including asthma. Recent individual studies suggested that nasal SA colonization may be positively associated with asthma.
objectiveTo examine relationships between nasal SA colonization and asthma prevalence and activity in adults.
methodsElectronic databases were searched for studies published until June 2018. Studies that reported nasal SA colonization prevalence and asthma outcome (prevalence and disease activity) in general adult populations or patients with chronic rhinosinusitis (CRS) were included. Random effects meta-analyses were performed to calculate pooled odds ratio (OR) of the relationships. Subgroup analysis was conducted for the presence of nasal polyps within CRS populations.
resultsA total of 21 cross-sectional studies were identified, and the data from 16 studies using culture methods for SA detection were meta-analyzed (5 general population-based studies and 11 studies of patients with CRS). In studies of general populations, nasal SA colonization had significant relationships with asthma prevalence (OR 1.19; 95% confidence interval [CI] 1.06-1.34; I
conclusionsThis study demonstrated modest but significant relationships between nasal SA colonization and asthma, supporting potential roles of SA in adult patients with asthma. Further longitudinal cohort and intervention studies are warranted to identify host determinants and to clarify causality of the relationships.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.