ArticleMayo Clinic proceedings2018
Aging, Obesity, and the Incidence of Diverticulitis: A Population-Based Study.
Article in Mayo Clinic proceedings, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Long-term outcomes in recurrent diverticulitis: a systematic review of treatment strategies and recurrence rates.International journal of colorectal disease · 2026Pooled it
- Safety of baricitinib for the treatment of rheumatoid arthritis over a median of 4.6 and up to 9.3 years of treatment: final results from long-term extension study and integrated database.Annals of the rheumatic diseases · 2022Pooled it
- The Trends of Complicated Acute Colonic Diverticulitis-A Systematic Review of the National Administrative Databases.Medicina (Kaunas, Lithuania) · 2019Pooled it
- Plasma Proteomic Signatures for Diverticulitis Risk Stratification.The Journal of surgical research · 2026Article
- Global hospital-based disease management of acute diverticulitis: a prospective, international cohort study.EClinicalMedicine · 2025Article
- Visceral Fat Quantified by a Fully Automated Deep-Learning Algorithm and Risk of Incident and Recurrent Diverticulitis.Diseases of the colon and rectum · 2025Article
- Prospective analysis of adiposity metrics for complicated acute colonic diverticulitis: Should WSES Classification and visceral adiposity be integrated for predictive analyses?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Pharmacovigilance analysis of orlistat adverse events based on the FDA adverse event reporting system (FAERS) database.Heliyon · 2024Article
- Diverticulitis in the Under-40 Population.Cureus · 2024Article
- Decreased Duration of Hospital Stays in Uncomplicated Diverticulitis With Initiation of Enteral Feeds Within 24 Hours.Journal of community hospital internal medicine perspectives · 2024Article
- Effects of sarcopenia and myosteatosis are alleviated in reduced port surgery for diverticulitis.International journal of colorectal disease · 2023Article
- The value of CA125 in predicting acute complicated colonic diverticulitis.International journal of colorectal disease · 2023Observational
- Venous thromboembolism following colectomy for diverticular disease: an English population-based cohort study.Langenbeck's archives of surgery · 2023Article
- Birth weight, childhood body mass index, and risk of diverticular disease in adulthood.International journal of obesity (2005) · 2023Article
- Seasonal variations in acute diverticular disease hospitalisations in New Zealand.International journal of colorectal disease · 2023Article
- Diverticulitis With Microperforation.Cureus · 2022Article
- Acute Diverticulitis in Young Patients: A Review of the Changing Epidemiology and Etiology.Digestive diseases and sciences · 2022Review
- Article
- Small Fiber Neuropathy Incidence, Prevalence, Longitudinal Impairments, and Disability.Neurology · 2021Article
- Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo understand why the population-based incidence of diverticulitis has increased over time, we studied temporal changes in age, body mass index (BMI), and diverticulitis in Olmsted County, Minnesota. PARTICIPANTS AND
methodsWe compared the BMIs of 2967 patients with diverticulitis and 9795 people without diverticulitis from January 1, 1980, through December 31, 2007. Because BMI is a surrogate for adipose tissue, computed tomographic estimations of abdominal fat content were compared between 381 diverticulitis cases and 381 age- and sex-matched controls.
resultsBetween 1980 and 2007, the prevalence of obesity increased from 12% to 49% in the population and from 19% to 40% in patients with diverticulitis (P<.001 for both). Temporal trends in age, BMI, and the increased incidence of diverticulitis in people with normal BMI accounted for 48%, 47%, and 20%, respectively, of corresponding trends in diverticulitis. The secular decline in the proportion of people with normal BMI was partly offset by an increased incidence of diverticulitis in such people. In the case-control study, BMI was greater in cases than in controls (P=.001). However, after incorporating abdominal visceral (odds ratio [OR], 2.4; 95% CI, 1.6-3.7) and subcutaneous (OR, 2.9; 95% CI, 1.7-5.2) fat content (both associated with diverticulitis), BMI was associated with lower risk (OR, 0.8; 95% CI, 0.7-0.8) of diverticulitis.
conclusionAging, increasing obesity, and the increased incidence of diverticulitis in people with normal BMI account for the temporal increase in diverticulitis. Rather than BMI per se, increased abdominal visceral and subcutaneous fat are independently associated with diverticulitis. The incidence of diverticulitis, which is among the most common gastrointestinal diagnoses in hospitalized patients, has increased markedly since 2000. This study suggests that aging, increasing obesity, and the increased incidence of diverticulitis in people with normal BMI account for the temporal increase in diverticulitis.
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