Evidence map›Paper›PMID 30192397›Full record

ArticleJournal of medical virology2019

Respiratory viral infections in infants with possible sepsis.

Kubra Aykac, Eda Karadag-Oncel, Sevgen Tanır Basaranoglu, Alpaslan Alp, Ali Bulent Cengiz, Mehmet Ceyhan, Ates Kara

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kubra AykacPediatric Infection Department, Hacettepe University Medicine Faculty Hospital, Ankara, Turkey.ORCID 0000-0002-0974-4765
Eda Karadag-OncelPediatric Infection Department, Hacettepe University Medicine Faculty Hospital, Ankara, Turkey.
Sevgen Tanır BasaranogluPediatric Infection Department, Hacettepe University Medicine Faculty Hospital, Ankara, Turkey.
Alpaslan AlpMicrobiology and Clinical Microbiology Department, Hacettepe University Medicine Faculty Hospital, Ankara, Turkey.
Ali Bulent CengizPediatric Infection Department, Hacettepe University Medicine Faculty Hospital, Ankara, Turkey.
Mehmet CeyhanPediatric Infection Department, Hacettepe University Medicine Faculty Hospital, Ankara, Turkey.
Ates KaraPediatric Infection Department, Hacettepe University Medicine Faculty Hospital, Ankara, Turkey.
Hacettepe University Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnowledge of infections leading to sepsis is needed to develop comprehensive infection prevention and sepsis, as well as early recognition and treatment strategies.The aim of this study was to investigate the etiology of sepsis and evaluate the proportion of respiratory viral pathogens in infants under two years of age with possible sepsis.

methodsThe prospective study was performed in two years. Multiplex reverse transcriptase polymerase chain reaction (RT-PCR) was performed to detect viral pathogens. All patients who were included in this study had sepsis symptoms as defined by the Surviving Sepsis Campaign.

resultsWe compared 90 patients with sepsis into three groups as patients (n = 33) who had only viral positivity in nasopharyngeal swab, patients (17) had proven bacterial infection with or without viral infection, and patients (40) without the pathogen detection. Human rhinovirus (16.7%) and influenza (7.8%) were the most commonly seen viruses. A cough was more common in the viral infection group than other groups ( P = 0.02) and median thrombocyte count was lower in the bacterial infection group than the others ( P = 0.01). Patients having bacterial sepsis had the longest duration of hospitalization than the other groups ( P = 0.04). During winter and spring seaons, patients with sepsis had more viral infection; however, in summer and autumn period, patients were mostly in a state that we could not prove infection agents ( P = 0.02).

conclusionsOur results suggest that respiratory tract viruses may play an important role in patients with sepsis and they should be kept in mind, especially during winter and spring seasons. In overall infection, viral respiratory viruses as a single pathogen with a detection rate of 36.6% in sepsis etiology.

Indexed as

Child, PreschoolFemaleHumansInfantMaleProspective StudiesRespiratory Tract InfectionsSepsisVirus DiseasesVirusesinfantrespiratory virusessepsis

Identifiers

PMID30192397
PMCPMC7166951
OpenAlexW2889949767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.