Evidence map›Paper›PMID 30192388›Full record

ArticleThe Journal of physiology2018

Effects of lorazepam and baclofen on short- and long-latency afferent inhibition.

Claudia V Turco, Jenin El-Sayes, Mitchell B Locke, Robert Chen, Steven Baker, Aimee J Nelson

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
  2. Distinct trajectories of response to prefrontal tDCS in major depression: results from a 3-arm randomized controlled trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Trial
  3. Article
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  7. Article
  8. Article
  9. Article
  10. Review
  11. Clinical diagnostic utility of transcranial magnetic stimulation in neurological disorders. Updated report of an IFCN committee.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Contemporary clinical neurophysiology applications in dystonia.Journal of neural transmission (Vienna, Austria : 1996) · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Claudia V TurcoDepartment of Kinesiology, McMaster University, Hamilton, ON, Canada.
Jenin El-SayesDepartment of Kinesiology, McMaster University, Hamilton, ON, Canada.
Mitchell B LockeDepartment of Kinesiology, McMaster University, Hamilton, ON, Canada.
Robert ChenDivision of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Steven BakerDivision of Physical Medicine and Rehabilitation, Department of Medicine, McMaster University, Hamilton, ON, Canada.
Aimee J NelsonDepartment of Kinesiology, McMaster University, Hamilton, ON, Canada.ORCID 0000-0003-1279-0815
McMaster University · CAUniversity of Toronto · CA

Funding

Gouvernement du Canada RGPIN 2015Natural Sciences and Engineering Research Council of Canada (Conseil de Recherches en Sciences Naturelles et en Génie du Canada) RGPIN 2015
6 · The paper itself

Abstract

key pointsShort-latency afferent inhibition (SAI) is modulated by GABA ABSTRACT: The afferent volley evoked by peripheral nerve stimulation has an inhibitory influence on transcranial magnetic stimulation induced motor evoked potentials. This phenomenon, known as afferent inhibition, occurs in two phases: short-latency afferent inhibition (SAI) and long-latency afferent inhibition (LAI). SAI exerts its inhibitory influence via cholinergic and GABAergic activity. The neurotransmitter receptors that mediate LAI remain unclear. The present study aimed to determine whether LAI is contributed by GABA

Indexed as

Neural InhibitionBaclofenGABA AgonistsHumansLorazepamMaleMedian NerveNeurons, AfferentReaction TimeYoung AdultBaclofenGABA AgonistsLorazepamafferent inhibitionGABATranscranial magnetic stimulation

Identifiers

PMID30192388
PMCPMC6209752
OpenAlexW2890964146

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.