Evidence map›Paper›PMID 30191807›Full record

ReviewMicrobiology spectrum2018

Dual-Function RNAs.

Medha Raina, Alisa King, Colleen Bianco, Carin K Vanderpool

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology spectrum, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Gene regulation inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Large Roles of Small Proteins.Annual review of microbiology · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Medha RainaDivision of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892.
Alisa KingDepartment of Microbiology, University of Illinois, Urbana, IL 61801.
Colleen BiancoDepartment of Microbiology, University of Illinois, Urbana, IL 61801.
Carin K VanderpoolDepartment of Microbiology, University of Illinois, Urbana, IL 61801.
University of Illinois Urbana-Champaign · USEunice Kennedy Shriver National Institute of Child Health and Human Development · US

Funding

Molecular Determinants of Regulatory Hierarchy for Bacterial Small RNAsR01GM092830 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI VANDERPOOL, CARIN K · 2010 to 2020
$2.8M
NIGMS NIH HHS R01 GM092830
6 · The paper itself

Abstract

Bacteria are known to use RNA, either as mRNAs encoding proteins or as noncoding small RNAs (sRNAs), to regulate numerous biological processes. However, a few sRNAs have two functions: they act as base-pairing RNAs and encode a small protein with additional regulatory functions. Thus, these so called "dual-function" sRNAs can serve as both a riboregulator and an mRNA. In some cases, these two functions can act independently within the same pathway, while in other cases, the base-pairing function and protein function act in different pathways. Here, we discuss the five known dual-function sRNAs-SgrS from enteric species, RNAIII and Psm-mec from

Indexed as

Gene Expression Regulation, BacterialBacillus subtilisBacteriaBacterial ProteinsBase PairingEscherichia coli ProteinsRNA, BacterialRNA, MessengerRNA, Small UntranslatedStaphylococcus aureusStreptococcus pyogenesBacterial ProteinsEscherichia coli ProteinsRNA, BacterialRNAIII, Staphylococcus aureusRNA, MessengerRNA, Small UntranslatedSgrT protein, E coli

Identifiers

PMID30191807
PMCPMC6130917
OpenAlexW2890617507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.