Evidence map›Paper›PMID 30191804›Full record

ReviewMicrobiology spectrum2018

RNA Localization in Bacteria.

Jingyi Fei, Cynthia M Sharma

Open access · hybridAbstract readReview
In one paragraph

Review in Microbiology spectrum, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Differential mRNA localization of karyopherin-β2 homologs inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. mRNA Localization to the Endoplasmic Reticulum in Plant Endosperm Cells.International journal of molecular sciences · 2022
    Review
  9. Review
  10. Article
  11. Recent advances in tools to map the microbiome.Current opinion in biomedical engineering · 2021
    Article
  12. Intracellular mRNA transport and localized translation.Nature reviews. Molecular cell biology · 2021
    Review
  13. Article
  14. Riboregulation in the Major Gastric PathogenFrontiers in microbiology · 2021
    Review
  15. Real-Time Messenger RNA Dynamics inFrontiers in microbiology · 2021
    Article
  16. Review
  17. mRNA localization is linked to translation regulation in theDevelopment (Cambridge, England) · 2020
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Jingyi FeiDepartment of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637.
Cynthia M SharmaChair of Molecular Infection Biology II, Institute of Molecular Infection Biology (IMIB), University of Würzburg, 97080 Würzburg, Germany.
University of Chicago · USUniversity of Würzburg · DE

Funding

Quantitative imaging of epitranscriptomic regulation mediated by RNA modificationDP2GM128185 · NIGMS · UNIVERSITY OF CHICAGO · PI FEI, JINGYI · 2017 to 2017
$2.4M
NIGMS NIH HHS DP2 GM128185
6 · The paper itself

Abstract

Diverse mechanisms and functions of posttranscriptional regulation by small regulatory RNAs and RNA-binding proteins have been described in bacteria. In contrast, little is known about the spatial organization of RNAs in bacterial cells. In eukaryotes, subcellular localization and transport of RNAs play important roles in diverse physiological processes, such as embryonic patterning, asymmetric cell division, epithelial polarity, and neuronal plasticity. It is now clear that bacterial RNAs also can accumulate at distinct sites in the cell. However, due to the small size of bacterial cells, RNA localization and localization-associated functions are more challenging to study in bacterial cells, and the underlying molecular mechanisms of transcript localization are less understood. Here, we review the emerging examples of RNAs localized to specific subcellular locations in bacteria, with indications that subcellular localization of transcripts might be important for gene expression and regulatory processes. Diverse mechanisms for bacterial RNA localization have been suggested, including close association to their genomic site of transcription, or to the localizations of their protein products in translation-dependent or -independent processes. We also provide an overview of the state of the art of technologies to visualize and track bacterial RNAs, ranging from hybridization-based approaches in fixed cells to

Indexed as

RNA TransportAptamers, NucleotideBacteriaBacterial ProteinsFluorescent DyesGene Expression Regulation, BacterialGreen Fluorescent ProteinsIn Situ Hybridization, FluorescenceMicroscopy, FluorescenceMolecular ImagingProtein TransportRecombinant Fusion ProteinsRibonucleasesRNA, BacterialRNA-Binding ProteinsStaining and LabelingAptamers, NucleotideBacterial ProteinsFluorescent DyesGreen Fluorescent ProteinsRecombinant Fusion ProteinsRibonucleasesRNA, BacterialRNA-Binding Proteins

Identifiers

PMID30191804
PMCPMC6264921
OpenAlexW2891252166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.