Evidence map›Paper›PMID 30191779›Full record

Trial reportPsychological medicine2019

Mamma Mia - A randomized controlled trial of an internet-based intervention for perinatal depression.

Silje Marie Haga, Filip Drozd, Carina Lisøy, Tore Wentzel-Larsen, Kari Slinning

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psychological medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04914299 (Positive Intelligence - Prospective Study Evaluating a Novel Mobile App Based Preventive Behavioral Intervention for Perinatal Mood Disorders), which is not on this map. Cited by 47 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 14 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04914299 nawithdrawnnot on this mapstarted 2021, after this paper: background citation

Positive Intelligence - Prospective Study Evaluating a Novel Mobile App Based Preventive Behavioral Intervention for Perinatal Mood Disorders

TypeinterventionalSponsorMassachusetts General HospitalRan2021 to 2022Enrolled0ConditionsPerinatal Depression, Perinatal AnxietyArmsApp-based "positive intelligence" intervention, Standard of care
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 14 syntheses or guidelines pooled it, 100 citations in OpenAlex.

  1. Positive psychology interventions during pregnancy: A systematic review.Applied psychology. Health and well-being · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Silje Marie HagaDepartment for Infant Mental Health,Regional Centre for Child and Adolescent Mental Health,Eastern and Southern Norway, Oslo,Norway.
Filip DrozdDepartment for Infant Mental Health,Regional Centre for Child and Adolescent Mental Health,Eastern and Southern Norway, Oslo,Norway.
Carina LisøyDepartment for Infant Mental Health,Regional Centre for Child and Adolescent Mental Health,Eastern and Southern Norway, Oslo,Norway.
Tore Wentzel-LarsenDepartment for Infant Mental Health,Regional Centre for Child and Adolescent Mental Health,Eastern and Southern Norway, Oslo,Norway.
Kari SlinningDepartment for Infant Mental Health,Regional Centre for Child and Adolescent Mental Health,Eastern and Southern Norway, Oslo,Norway.
Center for Child and Adolescent Mental Health, Eastern and Southern Norway · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies suggest that 10-15% of perinatal women experience depressive symptoms. Due to the risks, problems with detection, and barriers to treatment, effective universal preventive interventions are needed. The aim of this study was to assess the effectiveness of an automated internet intervention ('Mamma Mia') on perinatal depressive symptoms. Mamma Mia is tailored specifically to the perinatal phase and targets risk and protective factors for perinatal depressive symptoms.

methodsA total of 1342 pregnant women were randomized to an intervention ('Mamma Mia') and control group. Data were collected at gestational week (gw) 21-25, gw37, 6 weeks after birth, and 3 and 6 months after birth. We investigated whether (1) the intervention group displayed lower levels of depressive symptoms compared with the control group, (2) the effect of Mamma Mia changed over time, (3) the effect on depressive symptoms was moderated by baseline depressive symptoms, previous depression, and parity, and (4) this moderation changed by time. Finally, we examined if the prevalence of mothers with possible depression [i.e. Edinburgh Postnatal Depression Scale (EPDS)-score ⩾10] differed between the intervention and control group.

resultsParticipants in the Mamma Mia group displayed less depressive symptoms than participants in the control group during follow-up [F(1) = 7.03, p = 0.008]. There were indications that the effect of Mamma Mia was moderated by EPDS score at baseline. The prevalence of women with EPDS-score ⩾10 was lower in the Mamma Mia group at all follow-up measurements.

conclusionsThe study demonstrated the effects of the automated web-based universal intervention Mamma Mia on perinatal depressive symptoms.

Indexed as

Internet-Based InterventionOutcome Assessment, Health CarePsychotherapyAdultDepressive DisorderFemaleFollow-Up StudiesHumansPregnancyPregnancy ComplicationsInternet interventionlinear mixed effects modelsperinatal depressionrandomized controlled trialuniversal prevention

Identifiers

PMID30191779
PMCPMC6650775
OpenAlexW2891989723

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.