Evidence map›Paper›PMID 30191746›Full record

ReviewJournal of biological rhythms2018

Light, Alertness, and Alerting Effects of White Light: A Literature Overview.

Renske Lok, Karin C H J Smolders, Domien G M Beersma, Yvonne A W de Kort

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of biological rhythms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07761611 (Evaluation of Fatigue and Mitigations During Long-haul Operations), which is not on this map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07761611 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of Fatigue and Mitigations During Long-haul Operations

TypeinterventionalSponsorNational Aeronautics and Space Administration (NASA)Ran2026 to 2029Enrolled118ConditionsAlertness, Fatigue, Mood, and Performance, Calorie Restriction and Light InterventionArmsCaloric restriction, Light exposure
3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

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  8. bioRxiv : the preprint server for biology · 2026
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  17. Pathophysiological Models of Hypersomnolence Associated With Depression.Biological psychiatry global open science · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Renske LokChronobiology Unit, Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, the Netherlands.
Karin C H J SmoldersHuman-Technology Interaction, School of Innovation Sciences, Eindhoven University of Technology, Eindhoven, the Netherlands.
Domien G M BeersmaChronobiology Unit, Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, the Netherlands.
Yvonne A W de KortHuman-Technology Interaction, School of Innovation Sciences, Eindhoven University of Technology, Eindhoven, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light is known to elicit non-image-forming responses, such as effects on alertness. This has been reported especially during light exposure at night. Nighttime results might not be translatable to the day. This article aims to provide an overview of (1) neural mechanisms regulating alertness, (2) ways of measuring and quantifying alertness, and (3) the current literature specifically regarding effects of different intensities of white light on various measures and correlates of alertness during the daytime. In general, the present literature provides inconclusive results on alerting effects of the intensity of white light during daytime, particularly for objective measures and correlates of alertness. However, the various research paradigms employed in earlier studies differed substantially, and most studies tested only a limited set of lighting conditions. Therefore, the alerting potential of exposure to more intense white light should be investigated in a systematic, dose-dependent manner with multiple correlates of alertness and within one experimental paradigm over the course of day.

Indexed as

LightAttentionCircadian RhythmElectroencephalographyHumansPhotic StimulationWakefulnessalertnessdaytimelightneural mechanismsquantification

Identifiers

PMID30191746
PMCPMC6236641

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.