Evidence map›Paper›PMID 30191571›Full record

ArticleMedical physics2018

A framework for performance characterization of energy-resolving photon-counting detectors.

Mats Persson, Paurakh L Rajbhandary, Norbert J Pelc

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Framework for evaluating photon-counting detectors under pile-up conditions.Journal of medical imaging (Bellingham, Wash.) · 2024
    Article
  2. Article
  3. Spectral Photon Counting CT: Imaging Algorithms and Performance Assessment.IEEE transactions on radiation and plasma medical sciences · 2021
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mats PerssonDepartments of Bioengineering and Radiology, Stanford University, Stanford, CA, 94305, USA.
Paurakh L RajbhandaryDepartments of Electrical Engineering and Radiology, Stanford University, Stanford, CA, 94305, USA.
Norbert J PelcDepartments of Bioengineering, Radiology and Electrical Engineering, Stanford University, Stanford, CA, 94305, USA.
Stanford University · US

Funding

High dose efficiency CT SystemU01EB017140 · NIBIB · STANFORD UNIVERSITY · PI EDIC, PETER, PELC, NORBERT J. · 2014 to 2018
$5.4M
NIBIB NIH HHS U01 EB017140NIH HHS U01 EB01714003
6 · The paper itself

Abstract

purposePhoton-counting, energy-resolving detectors are subject to intense research interest, and there is a need for a general framework for performance assessment of these detectors. The commonly used linear-systems theory framework, which measures detector performance in terms of noise-equivalent quanta (NEQ) and detective quantum efficiency (DQE) is widely used for characterizing conventional x-ray detectors but does not take energy-resolving capabilities into account. The purpose of this work is to extend this framework to encompass energy-resolving photon-counting detectors and elucidate how the imperfect energy response and other imperfections in real-world detectors affect imaging performance, both for feature detection and for material quantification tasks.

methodWe generalize NEQ and DQE to matrix-valued quantities as functions of spatial frequency, and show how these matrices can be calculated from simple Monte Carlo simulations. To demonstrate how the new metrics can be interpreted, we compute them for simplified models of fluorescence and Compton scatter in a photon-counting detector and for a Monte Carlo model of a CdTe detector with

resultsOur results show that the ideal-linear-observer performance for any detection or material quantification task can be calculated from the proposed generalized NEQ and DQE metrics. We also demonstrate that the proposed NEQ metric is closely related to a generalized version of the Cramér-Rao lower bound commonly used for assessing material quantification performance. Off-diagonal elements in the NEQ and DQE matrices are shown to be related to loss of energy information due to imperfect energy resolution. The Monte Carlo model of the CdTe detector predicts a zero-frequency dose efficiency relative to an ideal detector of 0.86 and 0.65 for detecting water and bone, respectively. When the task instead is to quantify these materials, the corresponding values are 0.34 for water and 0.26 for bone.

conclusionsWe have developed a framework for assessing the performance of photon-counting energy-resolving detectors and shown that the matrix-valued NEQ and DQE metrics contain sufficient information for calculating the dose efficiency for both detection and quantification tasks, the task having any spatial and energy dependence. This framework will be beneficial for the development and optimization of photon-counting x-ray detectors.

Indexed as

PhotonsModels, TheoreticalRadiometryScattering, RadiationCramér-Rao lower bounddetective quantum efficiencylinear-systems theorynoise-equivalent quantaphoton countingspectral imagingx-ray imaging

Identifiers

PMID30191571
PMCPMC6234069
OpenAlexW2789502837

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.