Evidence map›Paper›PMID 30191447›Full record

ArticleLa Radiologia medica2019

Contrast analysis of the relationship between the HRCT sign and new pathologic classification in small ground glass nodule-like lung adenocarcinoma.

You Meng, Chen-Lu Liu, Qing Cai, Yu-Ying Shen, Shuang-Qing Chen

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In one paragraph

Article in La Radiologia medica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  4. Quantitative parameters of HRCT target scan to predict the risk of lung adenocarcinoma based on the detection of lung ground-glass nodules.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
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  18. [Expert Consensus for Thermal Ablation of Pulmonary Subsolid Nodules (2021 Edition)].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

You MengDepartment of Oncology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215001, China.
Chen-Lu LiuDepartment of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, No. 16, bai-ta-xi Road, Suzhou, 215001, Jiangsu Province, China.
Qing CaiDepartment of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, No. 16, bai-ta-xi Road, Suzhou, 215001, Jiangsu Province, China.
Yu-Ying ShenDepartment of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, No. 16, bai-ta-xi Road, Suzhou, 215001, Jiangsu Province, China.
Shuang-Qing ChenDepartment of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, No. 16, bai-ta-xi Road, Suzhou, 215001, Jiangsu Province, China. sznaonao@163.com.ORCID http://orcid.org/0000-0002-1504-4773
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo perform contrast analysis of the relationship between high-resolution computed tomography (HRCT) signs and new pathologic classification of small GGNs-like lung adenocarcinoma. MATERIALS AND

methodsThe HRCT data from 145 pathologically confirmed cases of small GGNs of lung adenocarcinoma were analysed retrospectively. The 145 cases of GGNs were divided into pre-invasive (PI) group (n = 46), micro-invasive adenocarcinoma (MIA) group (n = 48), and invasive adenocarcinoma (IAC) group (n = 51). HRCT imaging sign of GGNs in each group was assessed and compared.

resultsSignificant differences in GGN size were found among the three groups (P < 0.05). The presence of a tumour-lung interface in the MIA and IAC groups was significantly higher than that in the PI group (P < 0.05), but no significant difference was found between the MIA and IAC groups. The presence of a pleural indentation sign in the IAC group was significantly higher than that in the other two groups (P < 0.05), but no significant difference was noted between the latter two groups. Significant differences were found in the lobulated and spicule signs among the three groups (P < 0.05). The presence of a microvascular sign in the MIA and IAC groups was significantly higher than that in the PI group (P < 0.05). No significant difference was found in the GGN density, vacuole sign, air bronchus sign and notch sign among the three groups.

conclusionsThe HRCT signs of GGNs could be used to differentiate among pre-invasive lesions, micro-invasive lesions and invasive lung adenocarcinoma.

Indexed as

Adenocarcinoma of LungAdultAgedAged, 80 and overFemaleHumansLung NeoplasmsMaleMiddle AgedMultiple Pulmonary NodulesNeoplasm InvasivenessRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesTomography, X-Ray ComputedGround glass noduleHigh-resolution computed tomographyLung adenocarcinomaPathologic classification

Identifiers

PMID30191447
OpenAlexW2891950404

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.