Evidence map›Paper›PMID 30191438›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020

Multiparametric assessment of left atrial remodeling using

Michael Ghannam, Hong Jun Yun, Edward P Ficaro, Hamid Ghanbari, John J Lazarus, Matthew Konerman, Ravi V Shah, Richard Weinberg, James R Corbett, Hakan Oral and 1 more

Abstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Molecular phenotyping of atrial remodeling in atrial fibrillation usingThe international journal of cardiovascular imaging · 2026
    Article
  2. Additional Value of Cardiac Assessment With OncologicReviews in cardiovascular medicine · 2026
    Article
  3. Article
  4. Left Atrial Remodeling Identification and Catheter Ablation Outcomes WithJournal of the American Heart Association · 2025
    Article
  5. Article
  6. Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2020: positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Review
  7. New trials for assessment of left atrial dysfunction by FDG-PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  8. Mapping and Imaging in Non-paroxysmal AF.Arrhythmia & electrophysiology review · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Michael GhannamDepartment of Medicine (Division of Cardiovascular Medicine), University of Michigan, 1500 E. Medical Center Dr. SPC 5873, Ann Arbor, MI, 48109, USA.
Hong Jun YunDepartment of Medicine (Division of Cardiovascular Medicine), University of Michigan, 1500 E. Medical Center Dr. SPC 5873, Ann Arbor, MI, 48109, USA.
Edward P FicaroINVIA Medical Imaging Solutions, Ann Arbor, MI, USA.
Hamid GhanbariDepartment of Medicine (Division of Cardiovascular Medicine), University of Michigan, 1500 E. Medical Center Dr. SPC 5873, Ann Arbor, MI, 48109, USA.
John J LazarusDepartment of Medicine (Division of Cardiovascular Medicine), University of Michigan, 1500 E. Medical Center Dr. SPC 5873, Ann Arbor, MI, 48109, USA.
Matthew KonermanDepartment of Medicine (Division of Cardiovascular Medicine), University of Michigan, 1500 E. Medical Center Dr. SPC 5873, Ann Arbor, MI, 48109, USA.
Ravi V ShahDepartment of Medicine (Division of Cardiovascular Medicine), Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Richard WeinbergDepartment of Medicine (Division of Cardiovascular Medicine), University of Michigan, 1500 E. Medical Center Dr. SPC 5873, Ann Arbor, MI, 48109, USA.
James R CorbettDepartment of Medicine (Division of Cardiovascular Medicine), University of Michigan, 1500 E. Medical Center Dr. SPC 5873, Ann Arbor, MI, 48109, USA.
Hakan OralDepartment of Medicine (Division of Cardiovascular Medicine), University of Michigan, 1500 E. Medical Center Dr. SPC 5873, Ann Arbor, MI, 48109, USA.
Venkatesh L MurthyDepartment of Medicine (Division of Cardiovascular Medicine), University of Michigan, 1500 E. Medical Center Dr. SPC 5873, Ann Arbor, MI, 48109, USA. vlmurthy@med.umich.edu.

Funding

Implications of metabolism on healthy aging in African and Caucasian Americans: the Health ABC studyR01AG059729 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MURTHY, VENKATESH LOCHARLA, NEWMAN, ANNE B. · 2018 to 2022
$3.1M
Molecular markers of early cardiometabolic health transitions in the CARDIA studyR01HL136685 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MURTHY, VENKATESH LOCHARLA, SHAH, RAVI · 2017 to 2021
$2.6M
Novel Techniques for Evaluating and Assessing Symptoms, Affect. Heart Rhythm and Functional Status in Patients with Atrial Fibrillation: miAfib ProjectK23HL135397 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GHANBARI, HAMID · 2018 to 2022
$983k
NHLBI NIH HHS K23 HL135397NHLBI NIH HHS R01 HL136685NIA NIH HHS R01 AG059729
6 · The paper itself

Abstract

backgroundLeft atrial (LA) remodeling is associated with structural, electric, and metabolic LA changes. Integrated evaluation of these features in vivo is lacking.

methodsPatients undergoing

results117 patients were included (76% men, age 66.4 ± 11.0, ejection fraction (EF) 25[22-35]%) including those with SR (n = 48), PAF (n = 55), and PerAF (n = 14). Patients with any AF had increased SUVmean (2.3[1.5-2.4] vs 2.0[1.5-2.5], P = 0.006), SUVmax (4.4[2.8-6.7] vs 3.2[2.3-4.3], P < 0.001), uptake coefficient of variation (CoV) 0.28[0.22-0.40] vs 0.25[0.2-0.33], P < 0.001), and hypometabolic scar (32%[14%-53%] vs 16.5%[0%-38.5%], P = 0.01). AF burden correlated with increased SUVmean, SUVmax, CoV, and scar independent of age, gender, EF, or LA size (P < 0.03 for all).

conclusionsLA structure and metabolism can be assessed using FDG PET/CT. Greater AF burden correlates with the increased LA metabolism and scar.

Indexed as

Fluorodeoxyglucose F18RadiopharmaceuticalsAgedAged, 80 and overAtrial FibrillationAtrial RemodelingCardiac Imaging TechniquesFemaleHeart AtriaHumansMaleMiddle AgedPilot ProjectsPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18RadiopharmaceuticalscardiomyopathyechoMetabolicPET

Identifiers

PMID30191438
PMCPMC6411463

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.