Evidence map›Paper›PMID 30191341›Full record

ArticleThe AAPS journal2018

In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance.

Yasuhiro Tsume, Sanjaykumar Patel, Nikoletta Fotaki, Christel Bergstrӧm, Gordon L Amidon, James G Brasseur, Deanna M Mudie, Duxin Sun, Marival Bermejo, Ping Gao and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The AAPS journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yasuhiro TsumeCollege of Pharmacy, The University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109, USA. ytsume@umich.edu.
Sanjaykumar PatelMerck & Co., Inc., 126 E Lincoln Ave, Rahway, New Jersey, 07065, USA.
Nikoletta FotakiDepartment of Pharmacy and Pharmacology, University of Bath, Bath, UK.
Christel BergstrӧmDepartment of Pharmacy, Uppsala University, Uppsala, Sweden.
Gordon L AmidonCollege of Pharmacy, The University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109, USA.
James G BrasseurAerospace Engineering Sciences, University of Colorado, Boulder, Colorado, USA.
Deanna M MudieResearch and Development, Lonza, Bend, Oregon, USA.
Duxin SunCollege of Pharmacy, The University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109, USA.
Marival BermejoUniversidad Miguel Hernández de Elche, Elche, Spain.
Ping GaoAbbvie, Inc., Chicago, Illinois, USA.
Wei ZhuMerck & Co., Inc., West Point, Pennsylvania, 19486, USA.
David C SperryEli Lilly and Company, Indianapolis, Indiana, 46285, USA.
Maria VertzoniDepartment of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece.
Neil ParrottF. Hoffmann-La Roche, Ltd., Roche Innovation Center, Basel, Switzerland.
Robert LionbergerFood and Drug Administration, Silver Spring, Maryland, 21201, USA.
Atsushi KambayashiAstellas Pharma Inc., Shizuoka, Japan.
Andre HermansMerck & Co., Inc., West Point, Pennsylvania, 19486, USA.
Xujin LuBristol-Myers Squibb Company, New Brunswick, New Jersey, 08903, USA.
Gregory E AmidonCollege of Pharmacy, The University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109, USA.

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Alexey I Nesvizhskii · 1988 to 2026
$178.2M
NCI NIH HHS P30 CA046592
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug DevelopmentDrug LiberationModels, BiologicalAdministration, OralChemistry, PharmaceuticalComputer SimulationCongresses as TopicGastrointestinal AbsorptionGastrointestinal ContentsHumansHydrodynamicsHydrogen-Ion ConcentrationPharmaceutical PreparationsSolubilityPharmaceutical Preparationsdissolutionformulation predictionin vivo predictionsimulation

Identifiers

PMID30191341
PMCPMC8830932

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.