ArticleEuropean child & adolescent psychiatry2019
Trajectories of behavior, attention, social and emotional problems from childhood to early adulthood following extremely preterm birth: a prospective cohort study.
Article in European child & adolescent psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.
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Who cites it
60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- The impact of premature birth and low birth weight on motor, visual, and cognitive skills and mental health in adolescence: a systematic review and meta-analysis.European child & adolescent psychiatry · 2026Pooled it
- ADHD symptoms and diagnosis in adult preterms: systematic review, IPD meta-analysis, and register-linkage study.Pediatric research · 2023Pooled it
- Cortisol awakening response and developmental outcomes at 6-7 years in children born extremely preterm.Pediatric research · 2023Trial
- IQ Was Not Improved by Post-Discharge Fortification of Breastmilk in Very Preterm Infants.Nutrients · 2022Trial
- Effects of Omega-3-6-9 fatty acid supplementation on behavior and sleep in preterm toddlers with autism symptomatology: Secondary analysis of a randomized clinical trial.Early human development · 2022Trial
- Relevance of prematurity and foetal growth restriction for romantic relationships, health-risk behaviours, and socio-economic outcomes in adulthood.European journal of public health · 2026Article
- Relationships between cerebral blood flow and cognition in young adults born very preterm and at term.Scientific reports · 2026Article
- Histological chorioamnionitis and neurodevelopment at 5 years of age among infants born very preterm: EPIPAGE-2 cohort study.Archives of disease in childhood. Fetal and neonatal edition · 2026Article
- Preconceptual care reduces risk of spontaneous preterm birth for select high-risk populations: A prospective study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Attention problems in children born very preterm: evidence from a performance-based measure.Pediatric research · 2025Article
- Association between skin-to-skin contact and cognition and behaviour at 5 years in children born at 24-31 weeks' gestation: a secondary analysis of a national population-based prospective cohort study.EClinicalMedicine · 2025Article
- Developmental trajectories of internalizing problems among individuals born very preterm/very low birthweight: early risk and resilience factors.European child & adolescent psychiatry · 2025Article
- Neonatal neurodevelopmental follow-up in the UK: a survey of current practice and future recommendations.BMC pediatrics · 2025Article
- Factors influencing participation in home, school, and community settings by 6- to 9-year-old children born preterm: a qualitative descriptive study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Psychobstetrics or obstetrical psychiatry: a new discipline?European child & adolescent psychiatry · 2025Article
- Sequelae of preterm birth over the lifespan: an exploratory analysis of behavioral problems in childhood and increased risk of major depression and anxiety in adulthood from a cohort study.EClinicalMedicine · 2025Article
- Mediating Effects of Executive Function on the Relationship between Sleep Problems and Emotional and Behavioral Problems among Preschoolers: Physical Activity as a Protective Factor.Child psychiatry and human development · 2025Article
- Trajectories of attention problems in preschoolers born very preterm.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Trajectories of social outcomes in individuals born very preterm from childhood to adolescence.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Changes in social relationships from 26 to 34 years of age in adults born very preterm.Paediatric and perinatal epidemiology · 2025Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
To investigate trajectories of behavior, attention, social and emotional problems to early adulthood in extremely preterm survivors compared to a term-born comparison group. Longitudinal analysis of a prospective, population-based cohort of 315 surviving infants born < 26 completed weeks of gestation recruited at birth in 1995, from the UK/Republic of Ireland, and a term-born comparison group recruited at age 6. The parent-report Strengths and Difficulties Questionnaire was completed at age 6, 11, 16 and 19 years. The Total Behavioral Difficulties Score was 4.81 points higher in extremely preterm individuals compared to their term-born peers over the period (95% CI 3.76-5.87, p < 0.001) and trajectories were stable in both groups. The impact of difficulties on home life, friendships, school or work and/or leisure activities was greater in the EPT group (RR 4.28, 95% CI 2.89-6.35, p < 0.001), and hyperactivity/inattention and peer problems accounted for the largest differences. A clinically significant behavioral screen at age 2.5 was associated with a higher Total Behavioral Difficulties Score from 6 years onwards in extremely preterm participants (Mean difference 6.90, 95% CI 5.01-8.70, p < 0.0.01), as was moderate/severe cognitive impairment at last assessment (Mean difference: 4.27, 95% CI 2.76-5.77, p < 0.001). Attention, social and emotional problems in extremely preterm individuals persist into early adulthood with significant impact on daily life. A positive behavioral screen in infancy and moderate/severe cognitive impairment are associated with early adult outcomes.
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