Evidence map›Paper›PMID 30191310›Full record

SynthesisSurgical endoscopy2019

A systematic review and meta-analysis of metal versus plastic stents for drainage of pancreatic fluid collections: metal stents are advantageous.

Rebecca Saunders, Jayapal Ramesh, Silvia Cicconi, Jonathan Evans, Vincent S Yip, Michael Raraty, Paula Ghaneh, Robert Sutton, John P Neoptolemos, Christopher Halloran

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Endoscopic ultrasound-guided pancreatic pseudocyst drainage in pediatric patients.World journal of gastrointestinal pharmacology and therapeutics · 2026
    Article
  7. Review
  8. Review
  9. Pancreatic pseudocyst: The past, the present, and the future.World journal of gastrointestinal surgery · 2024
    Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Advancements in the endoscopic treatment of pancreatic fluid collections.Chronic diseases and translational medicine · 2020
    Review
  20. Alternative uses of lumen apposing metal stents.World journal of gastroenterology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Rebecca SaundersPancreatitis Research Group, Royal Liverpool University Hospital, Liverpool, UK.
Jayapal RameshGastroenterology, Royal Liverpool University Hospital, Liverpool, UK.
Silvia CicconiLiverpool Cancer Trials Unit, University of Liverpool, Liverpool, UK.
Jonathan EvansRadiology, Royal Liverpool University Hospital, Liverpool, UK.
Vincent S YipHPB Surgery, Barts Healthcare, London, UK.
Michael RaratyHPB Surgery, Barts Healthcare, London, UK.
Paula GhanehInstitute of Translational Medicine, University of Liverpool, Liverpool, UK.
Robert SuttonInstitute of Translational Medicine, University of Liverpool, Liverpool, UK.
John P NeoptolemosGeneral Surgery, Universitatsklinikum Heidelberg Chirurgische Klinik, Heidelberg, Germany.
Christopher HalloranInstitute of Translational Medicine, University of Liverpool, Liverpool, UK. Halloran@liverpool.ac.uk.
University of Liverpool · GBBarts Health NHS Trust · GBRoyal Liverpool University Hospital · GBUniversity Hospital Heidelberg · DE

Funding

Cancer Research UK 15957Department of Health 08/29/02Department of Health EME/15/20/01Department of Health PB-PG-0407-13363
6 · The paper itself

Abstract

backgroundThe use of fully covered metal stents (FCSEMS) and specifically designed lumen apposing metal stents for transmural drainage of pancreatic fluid collections has become widespread. A systematic review published in 2015 did not support the routine use of metal stents for drainage of pancreatic fluid collections. However, recent studies have shown conflicting data; therefore a systematic review and meta-analysis was performed.

methodWe conducted a database search for original comparative studies between plastic and metal stents. The random effects model was used to calculate pooled risk ratios (RR) with 95% confidence intervals (CI). Outcomes analysed were clinical success, adverse events and requirement of further intervention.

resultsThe search identified 936 studies, 7 studies with 681 (340 metal, 341 plastic) patients met inclusion criteria and were included in the meta-analysis. Clinical success was achieved in 93.8% versus 86.2% in the metal and plastic groups, respectively, RR 1.08 [95% CI 1.02-1.14]; p = 0.009. Adverse events were reduced for metal stents when compared with plastic (10.2% vs. 25.0%), RR 0.42 [95% CI 0.22-0.81]; p = 0.010. Metal stent usage reduced bleeding (2.8% vs. 7.9%), RR 0.37; [95% CI 0.18-0.75]; p = 0.006. Further intervention was required in 12.4% of patients in the metal stent group versus 26.7% for plastic stents, RR 0.54; [95% CI 0.22-1.29]; p = 0.165.

conclusionsThe use of metal stents for drainage of pancreatic fluid collections is associated with improved clinical success, fewer adverse events and reduced bleeding compared to plastic stents.

Indexed as

StentsAgedDrainageFemaleHemorrhageHumansMaleMiddle AgedOdds RatioPancreasPancreatic JuicePlasticsSelf Expandable Metallic StentsTreatment OutcomePlasticsDrainageEndoscopic ultrasound interventionMetal stentsPancreatic fluid collectionPancreatic pseudocystPlastic stents

Identifiers

PMID30191310
PMCPMC6484810
OpenAlexW2891051084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.