Evidence map›Paper›PMID 30191265›Full record

ArticleHerz2020

Cardiac rehabilitation therapy for coronary slow flow phenomenon.

W He, Y Huang, Y Zhang, W She, L Fang, Z Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Herz, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Exercise-based cardiac rehabilitation for coronary heart disease.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Coronary Slow-Flow Syndrome: A Review on Natural History of Disease and Best Practices.Research in heart yield and translational medicine · 2025
    Review
  3. Coronary slow flow research: a bibliometric analysis.European journal of medical research · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

W HeDepartment of Cardiology, First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Y HuangDepartment of Cardiology, First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Y ZhangDepartment of Cardiology, First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
W SheDepartment of Cardiology, First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
L FangDepartment of Cardiology, First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Z WangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China. whuwangzhuo@163.com.
First Affiliated Hospital of Xiamen University · CNRenmin Hospital of Wuhan University · CN

Funding

the Fundamental Research Funds for the Central Universities 2042018kf0102
6 · The paper itself

Abstract

objectiveTo evaluate the effectiveness of cardiac rehabilitation on coronary slow flow phenomenon.

methodIncluded were 30 consecutive patients from June 2015 to June 2017. A thrombolysis in myocardial infarction (TIMI) frame evaluation was used to estimate coronary blood flow velocity. All coronary angiography diameters were normal, but blood flow levels did not reach the TIMI level 3. All patients were treated with aspirin and rosuvastatin. Patients were randomly assigned to an experimental group (cardiac rehabilitation treatment group, n = 15) or a control group (normal treatment without cardiac rehabilitation, n = 15). Plasma low density lipoprotein cholesterol (LDL-C), triglyceride (TG), high-sensitivity C reactive protein (hs-CRP), homocysteine (Hcy) and arginine (Arg) expression levels were collected after admission. These indices were reviewed again after 20-30 weeks, improved subjective symptoms were evaluated by multiple outcome criteria (MOCs), and coronary angiography was used to evaluate the velocity of coronary artery blood flow.

resultThe expression levels of LDL-C and TG in the experimental group were significantly lower than those of the control group (both P < 0.01). The plasma levels of hs-CRP, Hcy and Arg were lower than those in the control group (all P < 0.01). In the experimental group, subjective symptoms of chest pain were significantly improved and the coronary artery blood flow velocity was significantly increased compared with the control group (P < 0.01).

conclusionCardiac rehabilitation can reduce the plasma levels of LDL-C, TG, hs-CRP, Hcy and Arg, significantly improve the symptoms of coronary slow flow phenomenon and accelerate the speed of coronary artery blood flow.

Indexed as

Cardiac RehabilitationNo-Reflow PhenomenonBlood Flow VelocityCoronary AngiographyCoronary CirculationCoronary VesselsC-Reactive ProteinHumansC-Reactive ProteinAngina pectorisBlood flow velocityCoronary arteriesCoronary heart diseaseMyocardial ischemia

Identifiers

PMID30191265
OpenAlexW2891431540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.