Evidence map›Paper›PMID 30191180›Full record

ArticleScience advances2018

Accelerated ex situ breeding of

Simon E Bull, David Seung, Christelle Chanez, Devang Mehta, Joel-Elias Kuon, Elisabeth Truernit, Anton Hochmuth, Irene Zurkirchen, Samuel C Zeeman, Wilhelm Gruissem and 1 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
20.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 168 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Manipulation ofPlants (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Creating a SuperiorFoods (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Functional Characterization of theInternational journal of molecular sciences · 2024
    Article
  17. Review
  18. Review
  19. Review
  20. Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Simon E BullPlant Biotechnology, Institute of Molecular Plant Biology, ETH Zurich, 8092 Zurich, Switzerland.ORCID 0000-0003-0506-6984
David SeungPlant Biochemistry, Institute of Molecular Plant Biology, ETH Zurich, 8092 Zurich, Switzerland.ORCID 0000-0003-3905-3647
Christelle ChanezPlant Biotechnology, Institute of Molecular Plant Biology, ETH Zurich, 8092 Zurich, Switzerland.ORCID 0000-0002-3432-4375
Devang MehtaPlant Biotechnology, Institute of Molecular Plant Biology, ETH Zurich, 8092 Zurich, Switzerland.ORCID 0000-0002-8911-1174
Joel-Elias KuonPlant Biotechnology, Institute of Molecular Plant Biology, ETH Zurich, 8092 Zurich, Switzerland.ORCID 0000-0003-1450-6996
Elisabeth TruernitPlant Biochemistry, Institute of Molecular Plant Biology, ETH Zurich, 8092 Zurich, Switzerland.
Anton HochmuthPlant Biochemistry, Institute of Molecular Plant Biology, ETH Zurich, 8092 Zurich, Switzerland.
Irene ZurkirchenPlant Biotechnology, Institute of Molecular Plant Biology, ETH Zurich, 8092 Zurich, Switzerland.
Samuel C ZeemanPlant Biochemistry, Institute of Molecular Plant Biology, ETH Zurich, 8092 Zurich, Switzerland.
Wilhelm GruissemPlant Biotechnology, Institute of Molecular Plant Biology, ETH Zurich, 8092 Zurich, Switzerland.
Hervé VanderschurenPlant Biotechnology, Institute of Molecular Plant Biology, ETH Zurich, 8092 Zurich, Switzerland.ORCID 0000-0003-2102-9737
Institute of Plant Biology · HUETH Zurich · CHUniversity of Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crop diversification required to meet demands for food security and industrial use is often challenged by breeding time and amenability of varieties to genome modification. Cassava is one such crop. Grown for its large starch-rich storage roots, it serves as a staple food and a commodity in the multibillion-dollar starch industry. Starch is composed of the glucose polymers amylopectin and amylose, with the latter strongly influencing the physicochemical properties of starch during cooking and processing. We demonstrate that CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9)-mediated targeted mutagenesis of two genes involved in amylose biosynthesis,

Indexed as

Arabidopsis ProteinsCRISPR-Cas SystemsCrops, AgriculturalGene EditingGerminationManihotMutagenesisPlant BreedingPlant ProteinsPlants, Genetically ModifiedStarchStarch SynthaseArabidopsis ProteinsFT protein, ArabidopsisPlant ProteinsStarchStarch Synthase

Identifiers

PMID30191180
PMCPMC6124905
OpenAlexW2889838251

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.