ArticleOpen forum infectious diseases2018
An Assessment of Inappropriate Antibiotic Use and Guideline Adherence for Uncomplicated Urinary Tract Infections.
Article in Open forum infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05702762 (Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting), which is not on this map. Cited by 64 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting
Who cites it
64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Escherichia coli Resistance to Fluoroquinolones in Community-Acquired Uncomplicated Urinary Tract Infection in Women: a Systematic Review.Antimicrobial agents and chemotherapy · 2020Pooled it
- A Systematic Review of Single-Dose Aminoglycoside Therapy for Urinary Tract Infection: Is It Time To Resurrect an Old Strategy?Antimicrobial agents and chemotherapy · 2019Pooled it
- Assessing Knowledge, Attitude, and Practices of Dentists on Antibiotic Use for Pediatric Dental Infections in Bangladesh: A Cross-Sectional Study.Health science reports · 2026Article
- Pharmacists' Management of Urinary Tract Infection Symptoms in Community Pharmacy: Counseling Practices and Attitudes Toward Antibiotic Therapy.Pharmacy (Basel, Switzerland) · 2026Article
- Analytical validation of a highly accurate and reliable next-generation sequencing-based urine assay.Microbiology spectrum · 2026Article
- Utilisation of antibiotics in the management of urinary tract infections among women of reproductive age at a district hospital in Ghana.Scientific reports · 2026Article
- Operational Research Improves Compliance with Treatment Guidelines for Empirical Management of Urinary Tract Infection: A Before-and-After Study from a Primary Health Facility in Ghana.Tropical medicine and infectious disease · 2025Article
- Antimicrobial resistance trends of methicillin-resistantJAC-antimicrobial resistance · 2025Article
- Appropriateness of Antibiotic Prescription Among Children Under 5 Years: A Cross-Sectional Study in a Ghanaian Regional Hospital.Health science reports · 2025Article
- Risk Factors for Antibiotic Exposure Post-Fecal Microbiota Transplantation for RecurrentOpen forum infectious diseases · 2025Article
- Compliance to international guidelines and rational use of antibiotics in urinary tract infections in a country without national guidance: a cross-sectional study.BMJ open quality · 2024Article
- Development of Predictive Models to Inform a Novel Risk Categorization Framework for Antibiotic Resistance in Escherichia coli-Caused Uncomplicated Urinary Tract Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Treatment Patterns and Adherence to Guidelines for Uncomplicated Urinary Tract Infection in Germany: A Retrospective Cohort Study.Infectious diseases and therapy · 2024Article
- Quality of Antibiotic Prescribing for Outpatient Cystitis in Adult Females.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024Article
- Overuse of antibiotics for urinary tract infections in pregnant refugees, Lebanon.Bulletin of the World Health Organization · 2024Article
- Antibiotic Stewardship Interventions for Urinary Tract Infections in Outpatient Settings: A Narrative Review.Infectious disease clinics of North America · 2024Review
- MACE and Hyperthyroidism Treated With Medication, Radioactive Iodine, or Thyroidectomy.JAMA network open · 2024Article
- Antibiotic utilization and symptom improvement in a retrospective cohort of women with urinary tract infection symptoms.International urogynecology journal · 2024Article
- Effectiveness of implementing a locally-developed guideline for antibiotic treatment of lower urinary tract infection in adults in Thailand.Scientific reports · 2023Article
- RETRACTED: Empowering Low- and Middle-Income Countries to Combat AMR by Minimal Use of Antibiotics: A Way Forward.Antibiotics (Basel, Switzerland) · 2023Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundIn 2011, The Infectious Diseases Society of America released a clinical practice guideline (CPG) that recommended short-course antibiotic therapy and avoidance of fluoroquinolones for uncomplicated urinary tract infections (UTIs). Recommendations from this CPG were rapidly disseminated to clinicians via review articles, UpToDate, and the Centers for Disease Control and Prevention website; however, it is unclear if this CPG had an impact on national antibiotic prescribing practices.
methodsWe performed a retrospective cohort study of outpatient and emergency department visits within a commercial insurance database between January 1, 2009, and December 31, 2013. We included nonpregnant women aged 18-44 years who had an
resultsWe identified 654 432 women diagnosed with UTI. The patient population was young (mean age, 31 years) and had few comorbidities. Fluoroquinolones, nonfirstline agents, were the most commonly prescribed antibiotic class both before and after release of the guidelines (45% vs 42%). Wide variation was observed in the duration of treatment, with >75% of prescriptions written for nonrecommended treatment durations. The CPG had minimal impact on antibiotic prescribing behavior by providers.
conclusionsInappropriate antibiotic prescribing is common for the treatment of UTIs. The CPG was not associated with a clinically meaningful change in national antibiotic prescribing practices for UTIs. Further interventions are necessary to improve outpatient antibiotic prescribing for UTIs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.