Evidence map›Paper›PMID 30191142›Full record

ArticleFrontiers in oncology2018

Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells.

Marina Mojena, Adrián Povo-Retana, Silvia González-Ramos, Victoria Fernández-García, Javier Regadera, Arturo Zazpe, Inés Artaiz, Paloma Martín-Sanz, Francisco Ledo, Lisardo Boscá

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Characterization of a Putrescine Transaminase FromFrontiers in bioengineering and biotechnology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Marina MojenaInstituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Madrid, Spain.
Adrián Povo-RetanaInstituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Madrid, Spain.
Silvia González-RamosInstituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Madrid, Spain.
Victoria Fernández-GarcíaInstituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Madrid, Spain.
Javier RegaderaDepartamento de Anatomía, Histología y Neurociencia, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain.
Arturo ZazpeR&D+i Department Faes-Farma, Avda Autonomía, Leioa, Spain.
Inés ArtaizR&D+i Department Faes-Farma, Avda Autonomía, Leioa, Spain.
Paloma Martín-SanzInstituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Madrid, Spain.
Francisco LedoR&D+i Department Faes-Farma, Avda Autonomía, Leioa, Spain.
Lisardo BoscáInstituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Madrid, Spain.
Faes Farma (Spain) · ESInstituto de Salud Carlos III · ESUniversidad Autónoma de Madrid · ESInstituto de Investigaciones Biomédicas Sols-Morreale · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanomas are heterogeneous and aggressive tumors, and one of the worse in prognosis. Melanoma subtypes follow distinct pathways until terminal oncogenic transformation. Here, we have evaluated a series of molecules that exhibit potent cytotoxic effects over the murine and human melanoma cell lines B16F10 and MalMe-3M, respectively, both

Indexed as

animal modelsapoptosiscellular lineschemotherapycytotoxicitymelanomametastasis

Identifiers

PMID30191142
PMCPMC6115490
OpenAlexW2888197954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.