Evidence map›Paper›PMID 30190867›Full record

ArticleMelanoma management2016

What are the therapeutic implications of increased collagen expression in melanoma cells treated with vemurafenib?

Constance E Brinckerhoff

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Melanoma management, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Constance E BrinckerhoffDepartment of Medicine, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.
Dartmouth College · US

Funding

IMMUNOBIOLOGY OF MYELOID AND LYMPHOID CELLST32AI007363 · NIAID · DARTMOUTH COLLEGE · PI Claudia V Jakubzick · 1990 to 2026
$9.5M
Invasive Behavior of Tumor Cells Producing Collagenase-1R01CA077267 · NCI · DARTMOUTH COLLEGE · PI BRINCKERHOFF, CONSTANCE E · 1999 to 2013
$2.6M
REGULATION OF METALLOPROTEINASE GENE EXPRESSIONR01AR026599 · NIAMS · DARTMOUTH COLLEGE · PI BRINCKERHOFF, CONSTANCE E · 1986 to 2011
$1.7M
Role of CXCR3 for CD8+ T cells in cancer immunotherapyR01CA134799 · NCI · UNIVERSITY OF VIRGINIA · PI MULLINS, DAVID W. · 2009 to 2013
$1.6M
CENTER FOR MOLECULAR, CELLULAR, AND TRANSLATIONAL IMMUNOLOGYP30RR032136 · NCRR · DARTMOUTH COLLEGE · PI GREEN, WILLIAM R · 2011 to 2011
$1.2M
NCI NIH HHS R01 CA077267NCI NIH HHS R01 CA134799NCRR NIH HHS P30 RR032136NIAID NIH HHS T32 AI007363NIAMS NIH HHS R01 AR026599
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BRAFV600EBRAFWTcarcinoma-activated fibroblastsfibroblastsMAPK signalingMEK inhibitorsTGF-βtumor microenvironmentvemurafenib/PLX4032

Identifiers

PMID30190867
PMCPMC6094651
OpenAlexW2330430974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.