Evidence map›Paper›PMID 30190842›Full record

ArticleMelanoma management2015

Electrochemotherapy in melanoma patients: a single institution experience.

Corrado Caracò, Ugo Marone, Ester Simeone, Antonio Maria Grimaldi, Gerardo Botti, Maurizio Del Giudice, Paolo Antonio Ascierto, Nicola Mozzillo

Abstract read
In one paragraph

Article in Melanoma management, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. The Diagnosis and Management of Cutaneous Metastases from Melanoma.International journal of molecular sciences · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Corrado CaracòMelanoma Department, Istituto Nazionale Tumori 'Fondazione Pascale' Napoli, Italy.
Ugo MaroneMelanoma Department, Istituto Nazionale Tumori 'Fondazione Pascale' Napoli, Italy.
Ester SimeoneMelanoma Department, Istituto Nazionale Tumori 'Fondazione Pascale' Napoli, Italy.
Antonio Maria GrimaldiMelanoma Department, Istituto Nazionale Tumori 'Fondazione Pascale' Napoli, Italy.
Gerardo BottiDivision of Pathology, Istituto Nazionale Tumori 'Fondazione Pascale' Napoli, Italy.
Maurizio Del GiudiceDivision of Anesthesiology, Istituto Nazionale Tumori 'Fondazione Pascale' Napoli, Italy.
Paolo Antonio AsciertoMelanoma Department, Istituto Nazionale Tumori 'Fondazione Pascale' Napoli, Italy.
Nicola MozzilloMelanoma Department, Istituto Nazionale Tumori 'Fondazione Pascale' Napoli, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study was undertaken to update the outcome of the treated lesions with electrochemotherapy (ECT) plus intravenous injection of bleomycin in patients with in-transit disease or distant cutaneous metastases in melanoma patients. PATIENTS &

methods89 patients with relapsed and refractory cutaneous melanoma metastases or in-transit disease were submitted to 126 treatments of ECT.

results34 patients (38.2%) had a partial response and 43 had a complete response (48.3%). 12 patients (13.5%) had no change or progressive disease. The objective response rate was 67.5%.

conclusionThe favorable outcome obtained in the present study demonstrates that ECT is a reliable, easy, fast and effective procedure showing benefits in terms of curative and palliative treatment for unresectable cutaneous lesions respecting the quality of life.

Indexed as

cutaneous metastaseselectrochemotherapyin-transitloco-regional treatmentsmelanoma

Identifiers

PMID30190842
PMCPMC6094613

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.