Evidence map›Paper›PMID 30190809›Full record

ReviewMelanoma management2014

No one should die of melanoma: a vision or impossible mission?

Iris Zalaudek, Elvira Moscarella, Caterina Longo, Aimilios Lallas, Giuseppe Argenziano, Rainer Hofmann-Wellenhof

Abstract readReview
In one paragraph

Review in Melanoma management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Iris ZalaudekDepartment of Dermatology, Medical University of Graz, Auenbruggerplatz 8, 8036 Graz, Austria.
Elvira MoscarellaSkin Cancer Unit, Arcispedale Santa Maria Nuova, IRCCS, Viale Risorgimento, 80, Reggio Emilia Reggio nell'Emilia, Italy.
Caterina LongoSkin Cancer Unit, Arcispedale Santa Maria Nuova, IRCCS, Viale Risorgimento, 80, Reggio Emilia Reggio nell'Emilia, Italy.
Aimilios LallasSkin Cancer Unit, Arcispedale Santa Maria Nuova, IRCCS, Viale Risorgimento, 80, Reggio Emilia Reggio nell'Emilia, Italy.
Giuseppe ArgenzianoSkin Cancer Unit, Arcispedale Santa Maria Nuova, IRCCS, Viale Risorgimento, 80, Reggio Emilia Reggio nell'Emilia, Italy.
Rainer Hofmann-WellenhofDepartment of Dermatology, Medical University of Graz, Auenbruggerplatz 8, 8036 Graz, Austria.
Ospedale Santa Maria · ITMedical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the incidence of early-stage melanoma has dramatically increased over the past decades, the incidence and mortality rates of thick melanomas have remained relatively stable during the same period. A number of alternative theories have been postulated in order to explain these divergent trends between thin and thick melanomas, among which is the question of whether nodular melanoma may originate in the dermis. This concept has gained support from recent improvements in the understanding of the origin of melanocytes and the morphological and molecular diversity of melanoma. A dermal origin would plausibly explain why efforts at improving the early detection of melanoma largely fail, as it implies an initially intradermal growth that is hidden from our eyes until clinical signs and symptoms become only secondarily apparent. In light of this, at the current stage, the vision that no one should die of melanoma is an impossible mission.

Indexed as

diagnosisepidemiologymelanomamelanomagenesisscreening

Identifiers

PMID30190809
PMCPMC6094643
OpenAlexW2095705531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.