Evidence map›Paper›PMID 30190661›Full record

ReviewEXCLI journal2018

Is autophagy associated with diabetes mellitus and its complications? A review.

Debalina Bhattacharya, Mainak Mukhopadhyay, Maitree Bhattacharyya, Parimal Karmakar

Open access · greenAbstract readReview
In one paragraph

Review in EXCLI journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 82 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. The Roles of Autophagy in Oxidative Stress.Archives of Razi Institute · 2025
    Review
  8. Article
  9. Proteostasis signatures in human diseases.PLoS computational biology · 2025
    Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. p66shc deficiency attenuates high glucose-induced autophagy dysfunction in Schwann cells.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Characterizing poorly controlled type 2 diabetes usingMetabolomics : Official journal of the Metabolomic Society · 2024
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Debalina BhattacharyaDepartment of Biochemistry, University of Calcutta, Kolkata-700019.
Mainak MukhopadhyayDepartment of Biotechnology, JIS University, Agarpara, Kolkata-700109.
Maitree BhattacharyyaDepartment of Biochemistry, University of Calcutta, Kolkata-700019.
Parimal KarmakarDepartment of Life Science and Biotechnology, Jadavpur University, Kolkata-700032.
University of Calcutta · INDepartment of Biotechnology · INJadavpur University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM) is an endocrine disorder. In coming decades it will be one of the leading causes of death globally. The key factors in the pathogenesis of diabetes are cellular injuries and disorders of energy metabolism leading to severe diabetic complications. Recent studies have confirmed that autophagy plays a pivotal role in diabetes and its complications. It has been observed that autophagy regulates the normal function of pancreatic β cells and insulin-target tissues, such as skeletal muscle, liver, and adipose tissue. This review will summarize the regulation of autophagy in diabetes and its complications, and explore how this process would emerge as a potential therapeutic target for diabetes treatment.

Indexed as

autophagycardiomyopathynephropathyretinopathyT2DMtype 2 diabetes mellitus

Identifiers

PMID30190661
PMCPMC6123605
OpenAlexW2982778318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.