ArticleScientific reports2018
Streptococcus mutans extracellular DNA levels depend on the number of bacteria in a biofilm.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
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- Real-time acid production and extracellular matrix formation in mature biofilms of threeBiofilm · 2024Article
- Exploring the influence of deposit mineral composition on biofilm communities in oil and gas systems.Frontiers in microbiology · 2024Article
- Effects of Novel Dental Composites onJournal of functional biomaterials · 2023Article
- The Antibacterial and Antifungal Activity of Chlorhexidine Diacetate Incorporated into Acrylic Resins Used in Provisional Restorations.Acta stomatologica Croatica · 2023Article
- Effects of Extracellular Self- and Nonself-DNA on the Freshwater MicroalgaPlants (Basel, Switzerland) · 2022Article
- Theranostic nanoplatforms of emodin-chitosan with blue laser light on enhancing the anti-biofilm activity of photodynamic therapy against Streptococcus mutans biofilms on the enamel surface.BMC microbiology · 2022Article
- Understanding the Matrix: The Role of Extracellular DNA in Oral Biofilms.Frontiers in oral health · 2021Review
- Characterization of Enterococcus faecalis in different culture conditions.Scientific reports · 2020Article
- Use of an oxygen planar optode to assess the effect of high velocity microsprays on oxygen penetration in a human dental biofilms in-vitro.BMC oral health · 2020Article
- Improvement in the Microbial Resistance of Resin-Based Dental Sealant by Sulfobetaine Methacrylate Incorporation.Polymers · 2020Article
- Modulation of Lipoteichoic Acids and Exopolysaccharides PreventsMolecules (Basel, Switzerland) · 2020Article
- CaBMC oral health · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Streptococcus mutans is a component of oral plaque biofilm that accumulates on the surface of teeth. The biofilm consists of extracellular components including extracellular DNA (eDNA). This study was conducted to investigate the factors that may affect the eDNA levels of S. mutans in biofilms. For the study, S. mutans UA159 biofilms were formed for 52 h on hydroxyapatite (HA) discs in 0% (w/v) sucrose +0% glucose, 0.5% sucrose, 1% sucrose, 0.5% glucose, 1% glucose, or 0.5% sucrose +0.5% glucose. Acidogenicity of S. mutans in the biofilms was measured after biofilm formation (22 h) up to 52 h. eDNA was collected after 52 h biofilm formation and measured using DNA binding fluorescent dye, SYBR Green I. Biofilms cultured in 0.5% sucrose or glucose had more eDNA and colony forming units (CFUs) and less exopolysaccharides (EPSs) than the biofilms cultured in 1% sucrose or glucose at 52 h, respectively. The biofilms formed in 0% sucrose +0% glucose maintained pH around 7, while the biofilms grown in 0.5% sucrose had more acidogenicity than those grown in 1% sucrose, and the same pattern was shown in glucose. In conclusion, the results of this study show that the number of S. mutans in biofilms affects the concentrations of eDNA as well as the acidogenicity of S. mutans in the biofilms. In addition, the thickness of EPS is irrelevant to eDNA aggregation within biofilms.
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