Evidence map›Paper›PMID 30190459›Full record

ReviewBlood cancer journal2018

Biological determinants of health disparities in multiple myeloma.

Cheryl Jacobs Smith, Stefan Ambs, Ola Landgren

Registry-linked trialAbstract readReview
In one paragraph

Review in Blood cancer journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05874193 (A Collaborative Community Effort Using Belantamab Mafodotin in Relapsed/Refractory Myeloma), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05874193 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Collaborative Community Effort Using Belantamab Mafodotin in Relapsed/Refractory Myeloma

TypeinterventionalSponsorCristiana Costa Chase, DORan2026 to 2028Enrolled33ConditionsRelapsed/Refractory Multiple MyelomaArmsBelantamab mafodotin
3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Establishment and Validation for Predicting the Death of Multiple Myeloma among Whites.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Flower-Like Plasma Cell Nuclei in Multiple MyelomaTurkish journal of haematology : official journal of Turkish Society of Haematology · 2021
    Article
  13. Review
  14. Health Equity Among Black Women in the United States.Journal of women's health (2002) · 2021
    Article
  15. Review
  16. Article
  17. Article
  18. Observational
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cheryl Jacobs SmithLaboratory of Human Carcinogenesis, Center for Cancer Research, National Institutes of Health, Bethesda, MD, USA.
Stefan AmbsLaboratory of Human Carcinogenesis, Center for Cancer Research, National Institutes of Health, Bethesda, MD, USA.
Ola LandgrenMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. landgrec@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) Core Grant (P30 CA008748); Dr. Landgren
6 · The paper itself

Abstract

Multiple myeloma is a rare plasma cell cancer, and incidence rates among patients of African descent are about twice those among patients of European descent. Rates of multiple myeloma vary among different populations, but the reasons for the racial disparities in multiple myeloma are largely unknown. Epidemiology has identified risk factors for multiple myeloma including race, advanced age, gender, family history, and exposure to different genetic toxins including radiation. Race and ancestry play a large role in predicting the risk for multiple myeloma, yet there exists a paucity of literature that explores the molecular contribution of race and ancestry to disease. In this review, we describe the relevant literature that describes the observed racial differences according to distinct tumor immunobiological and ancestral differences in populations.

Indexed as

Health Status DisparitiesPopulation GroupsDisease SusceptibilityFemaleHumansMaleMonoclonal Gammopathy of Undetermined SignificanceMultiple MyelomaPopulation SurveillancePrevalencePrognosis

Identifiers

PMID30190459
PMCPMC6127236

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.