Evidence map›Paper›PMID 30190434›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

A plant-responsive bacterial-signaling system senses an ethanolamine derivative.

Bruna G Coutinho, Emily Mevers, Amy L Schaefer, Dale A Pelletier, Caroline S Harwood, Jon Clardy, E Peter Greenberg

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
8.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Comparative genomic and functional analysis ofFrontiers in microbiology · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Structural basis for a bacterial Pip system plant effector recognition protein.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Insights into the early stages of plant-endophytic bacteria interaction.World journal of microbiology & biotechnology · 2021
    Review
  14. Article
  15. Article
  16. LuxR Solos in the Plant EndophyteApplied and environmental microbiology · 2020
    Article
  17. Review
  18. New Vocabulary for Bacterial Communication.Chembiochem : a European journal of chemical biology · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Bruna G CoutinhoDepartment of Microbiology, University of Washington, Seattle, WA 98195.
Emily MeversDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
Amy L SchaeferDepartment of Microbiology, University of Washington, Seattle, WA 98195.
Dale A PelletierBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830.
Caroline S HarwoodDepartment of Microbiology, University of Washington, Seattle, WA 98195.ORCID 0000-0003-4450-5177
Jon ClardyDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0003-0213-8356
E Peter GreenbergDepartment of Microbiology, University of Washington, Seattle, WA 98195; epgreen@uw.edu.ORCID 0000-0001-9474-8041
University of Washington · USHarvard University · USOak Ridge National Laboratory · US

Funding

Identification and characterization of gut microbial bioactive molecules that determine predisposition to autoimmune disease and atopyR01AT009708 · NCCIH · HARVARD MEDICAL SCHOOL · PI CLARDY, JON, XAVIER, RAMNIK J · 2017 to 2021
$3.3M
NCCIH NIH HHS R01 AT009708
6 · The paper itself

Abstract

Certain plant-associated Proteobacteria sense their host environment by detecting an unknown plant signal recognized by a member of a LuxR subfamily of transcription factors. This interkingdom communication is important for both mutualistic and pathogenic interactions. The

Indexed as

AcetamidesEndophytesEthanolamineGene Expression Regulation, BacterialMass SpectrometryPeriplasmic Binding ProteinsPlant Growth RegulatorsPlant LeavesPlant RootsPopulusPseudomonasRepressor ProteinsTrans-ActivatorsAcetamidesEthanolamineLuxR autoinducer binding proteinsN-(2-hydroxyethyl)-2-(2-hydroxyethylamino) acetamidePeriplasmic Binding ProteinsPlant Growth RegulatorsRepressor ProteinsTrans-ActivatorsethanolamineLuxR homologplant–microbe interactionsquorum sensingtranscription activator

Identifiers

PMID30190434
PMCPMC6166808
OpenAlexW2890195971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.