Evidence map›Paper›PMID 30190375›Full record

ArticleRNA (New York, N.Y.)2018

Inverted repeat structures are associated with essential and highly expressed genes on

Daniel P Reich, Brenda L Bass

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Daniel P ReichDepartment of Biochemistry, University of Utah, Salt Lake City, Utah 84112, USA.
Brenda L BassDepartment of Biochemistry, University of Utah, Salt Lake City, Utah 84112, USA.ORCID 0000-0003-1728-2254
University of Utah · US

Funding

DEVELOPMENTAL BIOLOGY TRAINING PROGRAMT32HD007491 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI James Alan Gagnon, Kristen M Kwan · 1995 to 2026
$8.0M
The Biology and Biochemistry of ADAR RNA Editing EnzymesR01GM044073 · NIGMS · UNIVERSITY OF UTAH · PI BASS, BRENDA L. · 1990 to 2020
$3.6M
Cellular double-stranded RNA as a signal of stress, immunity, and aging.DP1AG044162 · NIA · UNIVERSITY OF UTAH · PI BASS, BRENDA L. · 2012 to 2015
$3.0M
NIA NIH HHS DP1 AG044162NICHD NIH HHS T32 HD007491NIGMS NIH HHS R01 GM044073NIH HHS 5T32HD07491NIH HHS 8DP1AG044162NIH HHS RO1GM044073
6 · The paper itself

Abstract

Complementary sequences in cellular transcripts base-pair to form double-stranded RNA (dsRNA) structures. Because transposon-derived repeats often give rise to self-complementary sequences, dsRNA structures are prevalent in eukaryotic genomes, typically occurring in gene introns and untranslated regions (UTRs). However, the regulatory impact of double-stranded structures within genes is not fully understood. We used three independent methods to define loci in

Indexed as

AnimalsCaenorhabditis elegansGene Expression RegulationGene SilencingHistone CodeIntronsInverted Repeat SequencesNucleic Acid ConformationRNA, Double-StrandedRNA EditingRNA InterferenceUntranslated RegionsRNA, Double-StrandedUntranslated RegionsADARsdsRNAomegene regulationgenome organizationintronRNA editing

Identifiers

PMID30190375
PMCPMC6239182
OpenAlexW2891095256

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.