Evidence map›Paper›PMID 30190344›Full record

ArticleHaematologica2019

CD38 as a therapeutic target for adult acute myeloid leukemia and T-cell acute lymphoblastic leukemia.

Jyoti Naik, Maria Themeli, Regina de Jong-Korlaar, Ruud W J Ruiter, Pino J Poddighe, Huipin Yuan, Joost D de Bruijn, Gert J Ossenkoppele, Sonja Zweegman, Linda Smit and 4 more

Abstract readLetter
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Molecularly targeted therapy and immunotherapy in leukemias.Journal of hematology & oncology · 2026
    Review
  9. Article
  10. Review
  11. Review
  12. Where do immunotherapies stand in management of acute leukemia in adults?Hematology. American Society of Hematology. Education Program · 2025
    Review
  13. CAR-T cell therapy for cancer: current challenges and future directions.Signal transduction and targeted therapy · 2025
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jyoti NaikDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, the Netherlands.
Maria ThemeliDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, the Netherlands.
Regina de Jong-KorlaarDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, the Netherlands.
Ruud W J RuiterDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, the Netherlands.
Pino J PoddigheDepartment of Clinical Genetics, Amsterdam UMC, VU University Medical Center, Amsterdam, the Netherlands.
Huipin YuanKuros Biosciences BV, Bilthoven, the Netherlands.
Joost D de BruijnKuros Biosciences BV, Bilthoven, the Netherlands.
Gert J OssenkoppeleDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, the Netherlands.
Sonja ZweegmanDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, the Netherlands.
Linda SmitDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, the Netherlands.
Tuna MutisDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, the Netherlands.
Anton C M MartensDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, the Netherlands.
Niels W C J van de DonkDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, the Netherlands.
Richard W J GroenDepartment of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, the Netherlands r.groen@vumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Molecular Targeted TherapyADP-ribosyl Cyclase 1AdultAntineoplastic AgentsFemaleHumansLeukemia, Myeloid, AcuteMaleMembrane GlycoproteinsPrecursor T-Cell Lymphoblastic Leukemia-LymphomaTreatment OutcomeADP-ribosyl Cyclase 1Antineoplastic AgentsCD38 protein, humanMembrane Glycoproteins

Identifiers

PMID30190344
PMCPMC6395314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.