Evidence map›Paper›PMID 30190279›Full record

ArticleDevelopment (Cambridge, England)2018

Multiscale analysis of architecture, cell size and the cell cortex reveals cortical F-actin density and composition are major contributors to mechanical properties during convergent extension.

Joseph H Shawky, Uma L Balakrishnan, Carsten Stuckenholz, Lance A Davidson

Open access · greenAbstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Shape, Strain, and Stability: Epithelia Under High Strain.bioRxiv : the preprint server for biology · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Size-dependent osteogenesis of black phosphorus in nanocomposite hydrogel scaffolds.Journal of biomedical materials research. Part A · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Molecular and Mechanical Cues for Somite Periodicity.Frontiers in cell and developmental biology · 2021
    Review
  15. Review
  16. Review
  17. Review
  18. Convergent extension in the amphibian, Xenopus laevis.Current topics in developmental biology · 2020
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joseph H ShawkyDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Uma L BalakrishnanDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Carsten StuckenholzDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Lance A DavidsonDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA lad43@pitt.edu.ORCID 0000-0002-2956-0437
University of Pittsburgh · US

Funding

Training in Biomechanics in Regenerative MedicineT32EB003392 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WOO, SAVIO L-Y. · 2005 to 2020
$4.0M
The Biomechanics of morphogenesis in the frogR01HD044750 · NICHD · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI DAVIDSON, LANCE A. · 2005 to 2020
$3.8M
Biophysics of development buffering: Temperature as a tool to study how the cytosR21ES019259 · NIEHS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAVIDSON, LANCE A. · 2010 to 2011
$404k
NIBIB NIH HHS T32 EB003392NICHD NIH HHS R01 HD044750NIEHS NIH HHS R21 ES019259
6 · The paper itself

Abstract

The large-scale movements that construct complex three-dimensional tissues during development are governed by universal physical principles. Fine-grained control of both mechanical properties and force production is crucial to the successful placement of tissues and shaping of organs. Embryos of the frog

Indexed as

Cell SizeActinsAnimalsBiomechanical PhenomenaCell CountCell DifferentiationElastic ModulusEmbryo, NonmammalianFibrillinsImaging, Three-DimensionalLamininMesodermModels, BiologicalNeurulationXenopus laevisActinsFibrillinsLamininActin cross-linkersActomyosinBiomechanicsCell cycleCellular foamCentrifugationDissociationExtracellular matrixGerm layersMorphogenesisTissue architectureTissue mechanics

Identifiers

PMID30190279
PMCPMC6198471
OpenAlexW2890814055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.