Evidence map›Paper›PMID 30189863›Full record

ArticleBMC biology2018

Q&A: Array tomography.

Stephen J Smith

Abstract read
In one paragraph

Article in BMC biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Array tomography: trails to discovery.Methods in microscopy · 2024
    Article
  3. Review
  4. Article
  5. Volume electron microscopy.Nature reviews. Methods primers · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Volume electron microscopy: analyzing the lung.Histochemistry and cell biology · 2021
    Review
  10. Article
  11. Unobstructed Multiscale Imaging of Tissue Sections for Ultrastructural Pathology Analysis by Backscattered Electron Scanning Microscopy.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2020
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Stephen J SmithAllen Institute for Brain Science, Seattle, WA, USA. stephens@alleninstitute.org.

Funding

Synaptomes of Mouse and ManR01NS092474 · NINDS · ALLEN INSTITUTE · PI BURNS, RANDAL, SMITH, STEPHEN J · 2014 to 2018
$8.7M
Dynamics and molecular mechanism of synaptic connectivity change during learningR01MH104227 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ZUO, YI · 2014 to 2018
$2.1M
NIMH NIH HHS R01 MH104227NINDS NIH HHS R01 NS092474
6 · The paper itself

Abstract

Array tomography encompasses light and electron microscopy modalities that offer unparalleled opportunities to explore three-dimensional cellular architectures in extremely fine structural and molecular detail. Fluorescence array tomography achieves much higher resolution and molecular multiplexing than most other fluorescence microscopy methods, while electron array tomography can capture three-dimensional ultrastructure much more easily and rapidly than traditional serial-section electron microscopy methods. A correlative fluorescence/electron microscopy mode of array tomography furthermore offers a unique capacity to merge the molecular discrimination strengths of multichannel fluorescence microscopy with the ultrastructural imaging strengths of electron microscopy. This essay samples the first decade of array tomography, highlighting applications in neuroscience.

Indexed as

Cytological TechniquesElectron Microscope TomographyImaging, Three-DimensionalMicroscopy, Electron, ScanningMicroscopy, Fluorescence

Identifiers

PMID30189863
PMCPMC6127925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.