ArticleNeuroImage2018
Adolescents' brain-autonomic coupling during emotion processing.
Article in NeuroImage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Brain and Cognitive Development in Adolescents with Anorexia Nervosa: A Systematic Review of fMRI Studies.Nutrients · 2019Pooled it
- Elevated Galvanic Skin Response and Associated Brain Network Patterns in Youth at High Familial Risk for Bipolar Disorder.JAACAP open · 2026Article
- Contextualizing the adolescent social brain: Links to social health using data from the Adolescent Brain Cognitive Development Study.Developmental cognitive neuroscience · 2026Article
- Safety and stress-reducing effects of rosemary extract: an open-label trial and randomized double-blind crossover study.Journal of clinical biochemistry and nutrition · 2025Article
- Parasympathetic regulation and support from family and friends predict prosocial development in U.S. Mexican-origin adolescents.Developmental psychology · 2024Article
- Dampened autonomic nervous system responses to stress and substance use in adolescence.Stress and health : journal of the International Society for the Investigation of Stress · 2023Article
- Time course efficiency of MICE and HIIE on inhibitory control and HRV in adolescents with obesity and different cardiorespiratory fitness.Frontiers in psychology · 2023Article
- The impact of social disadvantage on autonomic physiology of latinx adolescents: The role of environmental risks.New directions for child and adolescent development · 2022Article
- Neural Response to Social Exclusion Moderates the Link Between Adolescent Anxiety Symptoms and Substance Use.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- High vagal tone and rapid extinction learning as potential transdiagnostic protective factors following childhood violence exposure.Developmental psychobiology · 2021Article
- Midcingulate Cortical Activations Interrelate Chronic Craving and Physiological Responses to Negative Emotions in Cocaine Addiction.Biological psychiatry global open science · 2021Article
- Direct replication of task-dependent neural activation patterns during sadness introspection in two independent adolescent samples.Human brain mapping · 2020Article
- Resting heart rate variability is negatively associated with mirror neuron and limbic response to emotional faces.Biological psychology · 2019Article
- Tuning of brain-autonomic coupling by prior threat exposure: Implications for internalizing problems in Mexican-origin adolescents.Development and psychopathology · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Autonomic nervous system (ANS) activity is a core component of emotion processing. The limbic system and medial prefrontal cortex play important roles in the regulation of ANS activity. However, the integration of brain activity and ANS activity has yet to be investigated in adolescents despite independent evidence of adolescents' heightened neural and physiological sensitivity to emotional stimuli. The present study examined the relations of ANS activity in the parasympathetic nervous system (PNS) and sympathetic nervous system (SNS) with brain activity during emotional face processing in adolescents. 135 adolescents (65 female; M = 17.15 yr, SD = 0.42) completed an emotional faces task during an fMRI scan while electrocardiography and skin conductance were recorded simultaneously. Using linear mixed-effect modelling, we tested the effect of change in respiratory sinus arrhythmia (RSA), a measure of PNS activity, and number of skin conductance responses (SCRs), a measure of SNS activity, on neural activity while adolescents viewed emotional faces. Greater RSA withdrawal, indicating decreased PNS activity, was associated with increased activation in the ventromedial prefrontal cortex (vmPFC). More SCRs, indicating greater SNS activity, were associated with decreased activation in several regions including the dorsomedial prefrontal cortex and increased activation in the left hippocampus. Left hippocampus-SCR coupling and vmPFC-RSA coupling predicted baseline SCR and RSA respectively. These findings implicate the hippocampus for potentiating SNS activity, document that regulation of SNS and PNS activity are coordinated with distinct regions of the medial prefrontal cortex, and suggest potential developmental differences in vmPFC regulation of PNS activity between adolescents and adults.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.