Evidence map›Paper›PMID 30189332›Full record

ArticleBrain and language2018

Global gray matter morphometry differences between children with reading disability, ADHD, and comorbid reading disability/ADHD.

Audreyana C Jagger-Rickels, Michelle Y Kibby, Jordan M Constance

Open access · greenAbstract read
In one paragraph

Article in Brain and language, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 5 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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  17. Learning Disorder Confers Setting-Specific Treatment Resistance for Children with ADHD, Predominantly Inattentive Presentation.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Audreyana C Jagger-RickelsSouthern Illinois University, Carbondale, United States.
Michelle Y KibbySouthern Illinois University, Carbondale, United States. Electronic address: mkibby@siu.edu.
Jordan M ConstanceSouthern Illinois University, Carbondale, United States.
Southern Illinois University Carbondale · US

Funding

Are Frontal Lobe Size and Executive Dysfunction Contributors to ADHD AND DyslexiaR15HD065627 · NICHD · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI KIBBY, MICHELLE Y · 2010 to 2011
$476k
Working Memory and Brain Morphology in Dyslexia and ADHDR03HD048752 · NICHD · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI KIBBY, MICHELLE Y · 2005 to 2006
$141k
NICHD NIH HHS R03 HD048752NICHD NIH HHS R15 HD065627
6 · The paper itself

Abstract

Extensive, yet disparate, research exists elucidating structural anomalies in individuals with Reading Disability (RD) or ADHD. Despite ADHD and RD being highly comorbid, minimal research has attempted to determine shared patterns of morphometry between these disorders. In addition, there is no published research examining the morphometry of comorbid RD and ADHD (RD/ADHD). Hence, we conducted voxel-based morphometry on the MRI scans of 106 children, ages 8-12 years, with RD, ADHD, or RD/ADHD, and typically developing controls. We found right caudate and superior frontal regions in both RD and ADHD, along with areas specific to RD and to ADHD that are consistent with current theories on these disorders. Perhaps most importantly, we found a potential neurobiological substrate for RD/ADHD. Further, our findings illustrate both shared and specific contributors to RD/ADHD, supporting two current theories on the comorbidity of RD and ADHD, thereby facilitating future work on potential etiologies of RD/ADHD.

Indexed as

ReadingAttention Deficit Disorder with HyperactivityChildComorbidityDyslexiaFemaleFollow-Up StudiesFrontal LobeGray MatterHumansMagnetic Resonance ImagingMaleADHDFrontal lobesMorphometryOccipital lobesReading disabilityReading disability/ADHDStriatumStructural neuroimagingThalamusVBM

Identifiers

PMID30189332
PMCPMC6940023
OpenAlexW2890396326

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.