ArticleSchizophrenia bulletin2019
Reduced Neural Sensitivity to Social vs Nonsocial Reward in Schizophrenia.
Article in Schizophrenia bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Transdiagnostic Comparison of Anticipated Hedonic Deficits: A Three-Level Meta-Analysis Across Schizophrenia, Depression, and Their Subclinical Individuals.PsyCh journal · 2026Pooled it
- Neurofunctional representations of instrumental learning in psychosis: a meta-analysis of neuroimaging studies.Psychological medicine · 2025Pooled it
- Common Neural Deficits in Social and Monetary Reinforcement Learning in Schizophrenia.Schizophrenia bulletin · 2026Article
- Differential impacts of audiovisual information on empathic accuracy in people with schizophrenia and high social anhedonia.Psychological medicine · 2026Article
- Blunted Ventral Striatal Reactivity to Social Reward Is Associated with More Severe Motivation and Pleasure Deficits in Psychosis.Schizophrenia bulletin · 2025Article
- Social Reward Learning Deficits and Concordant Brain Alterations in Rats Overexpressing Disrupted-in-Schizophrenia 1 (DISC1).The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A review of the effects of different types of social behaviors on the recruitment of neuropeptides and neurotransmitters in the nucleus accumbens.Frontiers in neuroendocrinology · 2025Review
- The Impact of Social Stress on Trustworthiness Judgments in Schizophrenia.PsyCh journal · 2025Article
- Motivation and Pleasure Deficits Undermine the Benefits of Social Affiliation in Psychosis.Clinical psychological science : a journal of the Association for Psychological Science · 2024Article
- Blunted ventral striatal reactivity to social reward is associated with more severe motivation and pleasure deficits in psychosis.Research square · 2024Article
- The SocialVidStim: a video database of positive and negative social evaluation stimuli for use in social cognitive neuroscience paradigms.Social cognitive and affective neuroscience · 2024Article
- Differential deficits in social versus monetary reinforcement learning in schizophrenia: Associations with facial emotion recognition.Journal of psychopathology and clinical science · 2024Article
- Social Motivation in Schizophrenia: What's Effort Got to Do With It?Schizophrenia bulletin · 2023Review
- Sex and pubertal influences on the neurodevelopmental underpinnings of schizophrenia: A case for longitudinal research on adolescents.Schizophrenia research · 2023Review
- Aberrant reward processing to positive versus negative outcomes across psychotic disorders.Journal of psychiatric research · 2022Article
- Neurexin1α knockout rats display oscillatory abnormalities and sensory processing deficits back-translating key endophenotypes of psychiatric disorders.Translational psychiatry · 2022Article
- Reduced neural activity when anticipating social versus nonsocial rewards in schizophrenia: Preliminary evidence from an ERP study.Schizophrenia research · 2022Article
- Rethinking delusions: A selective review of delusion research through a computational lens.Schizophrenia research · 2022Review
- Social anhedonia as a Disrupted-in-Schizophrenia 1-dependent phenotype.Scientific reports · 2022Article
- Neural, behavioural and real-life correlates of social context sensitivity and social reward learning during interpersonal interactions in the schizophrenia spectrum.The Australian and New Zealand journal of psychiatry · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundHuman beings find social stimuli rewarding, which is thought to facilitate efficient social functioning. Although reward processing has been extensively studied in schizophrenia, a few studies have examined neural processes specifically involved in social reward processing. This study examined neural sensitivity to social and nonsocial rewards in schizophrenia.
methodsTwenty-seven patients with schizophrenia and 25 community controls completed a One-Armed Bandit Task, an implicit reinforcement learning task, in the scanner. There were 2 conditions with an identical trial structure, one with social rewards and the other with nonsocial rewards. The data were analyzed using a region of interest (ROI) approach, focusing on the ventral striatum, ventromedial prefrontal cortex, and anterior cingulate cortex.
resultsAcross all 3 ROIs, patients showed reduced activation for social rewards compared to controls. However, the 2 groups showed comparable levels of activation for nonsocial rewards. Within the patient group, levels of neural activation in these ROIs during the social reward condition were associated with better performance.
conclusionsThis study found reduced neural sensitivity in patients with schizophrenia in key reward-processing regions for social but not for nonsocial rewards. These findings suggest a relatively specific social reward-processing deficit in schizophrenia during an implicit reinforcement learning task.
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