Evidence map›Paper›PMID 30188930›Full record

Observational studyPloS one2018

Features of patients with rheumatoid arthritis whose debut joint is a foot or ankle joint: A 5,479-case study from the IORRA cohort.

Koichiro Yano, Katsunori Ikari, Eisuke Inoue, Yu Sakuma, Takeshi Mochizuki, Naoko Koenuma, Haruki Tobimatsu, Eiichi Tanaka, Atsuo Taniguchi, Ken Okazaki and 1 more

Open access · goldAbstract readComparative StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Five-year radiographic and clinical outcomes after arthroscopic synovectomy of the ankle in rheumatoid arthritis: A clinical trial.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
    Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Joint-Preserving Surgery for Forefoot Deformities in Patients with Rheumatoid Arthritis: A Literature Review.International journal of environmental research and public health · 2021
    Review
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Koichiro YanoInstitute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
Katsunori IkariInstitute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.ORCID 0000-0001-9066-2005
Eisuke InoueInstitute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
Yu SakumaInstitute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
Takeshi MochizukiInstitute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
Naoko KoenumaInstitute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
Haruki TobimatsuInstitute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
Eiichi TanakaInstitute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
Atsuo TaniguchiInstitute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
Ken OkazakiInstitute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
Hisashi YamanakaInstitute of Rheumatology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
Tokyo Women's Medical University · JPSt. Marianna University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFoot and ankle joint disorders are serious issues for patients with rheumatoid arthritis (RA). We compared the differences between patients with RA whose first symptom involved a foot or ankle joint (FOOT group) versus other joints (non-FOOT group) within the Institute of Rheumatology, Rheumatoid Arthritis (IORRA) cohort in our institute. PATIENTS AND

methodsIn the IORRA survey conducted in April 2016, patients were invited to complete six questionnaires about their first symptom at RA onset, current foot or ankle symptoms, daily living activities, and mental health. Disease activity, clinical laboratory variables, functional disability, quality of life, use and ratio of anti-inflammatory and antirheumatic drugs, daily living activities and mental health were compared between the two groups.

resultsAmong 5,637 Japanese patients with RA who participated in the IORRA survey on April 2016, 5,479 (97.2%) responded to the questionnaire regarding their debut joint. Of these patients, 2,402 (43.8%) reported that their first symptom of RA involved a foot or ankle joint. The FOOT group (n = 2,164) had higher disease activity, higher disabilities, lower quality of life, lower activities of daily living, and poorer mental health and used anti-inflammatory drugs at a higher rate and at higher doses compared with the non-FOOT group (n = 2,164). On the other hand, the use of medications to suppress the disease activity of RA was similar between the groups.

conclusionClinicians should pay more attention to foot and ankle joints in daily practice so as not to underestimate the disease activity of RA.

Indexed as

Activities of Daily LivingAdultAgedAged, 80 and overAnkle JointAntirheumatic AgentsArthritis, RheumatoidCohort StudiesFemaleFoot JointsHumansJapanMaleMiddle AgedSurveys and QuestionnairesYoung AdultAntirheumatic Agents

Identifiers

PMID30188930
PMCPMC6126825
OpenAlexW2892010334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.