Evidence map›Paper›PMID 30188694›Full record

ArticleBioconjugate chemistry2019

mRNA Polyplexes with Post-Conjugated GALA Peptides Efficiently Target, Transfect, and Activate Antigen Presenting Cells.

Bo Lou, Stefaan De Koker, Chun Yin Jerry Lau, Wim E Hennink, Enrico Mastrobattista

Abstract read
In one paragraph

Article in Bioconjugate chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Tissue-specific gene delivery approaches.Bioengineering & translational medicine · 2026
    Review
  5. Review
  6. The strategies and advances of mRNA translation booster.Asian journal of pharmaceutical sciences · 2025
    Review
  7. Article
  8. Article
  9. Recent Advances in mRNA Delivery Systems for Cancer Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. mRNA vaccines and their delivery strategies: A journey from infectious diseases to cancer.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Review
  16. Acta pharmaceutica Sinica. B · 2024
    Review
  17. Review
  18. Review
  19. Antigen Delivery Systems: Past, Present, and Future.Biomolecules & therapeutics · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bo LouDepartment of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS) , Utrecht University , 3584CG Utrecht , The Netherlands.
Stefaan De KokerLaboratory of Molecular Immunology, Department of Biomedical Molecular Biology , Ghent University , 9052 Zwijnaarde , Belgium.
Chun Yin Jerry LauDepartment of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS) , Utrecht University , 3584CG Utrecht , The Netherlands.
Wim E HenninkDepartment of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS) , Utrecht University , 3584CG Utrecht , The Netherlands.ORCID 0000-0002-5750-714X
Enrico MastrobattistaDepartment of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS) , Utrecht University , 3584CG Utrecht , The Netherlands.ORCID 0000-0002-6745-2015

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccines based on mRNA have emerged as potent systems to elicit CD8

Indexed as

AnimalsCell LineClick ChemistryDendritic CellsGreen Fluorescent ProteinsMiceOvalbuminPeptidesPolymersRAW 264.7 CellsRNA, MessengerTransfectionenhanced green fluorescent proteinGALA peptideGreen Fluorescent ProteinsOvalbuminPeptidesPolymersRNA, Messenger

Identifiers

PMID30188694
PMCPMC6385079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.