Evidence map›Paper›PMID 30188494›Full record

ArticleJournal of occupational and environmental medicine2018

Experimental Woodsmoke Exposure During Exercise and Blood Oxidative Stress.

Bridget Peters, Christopher Ballmann, Tiffany Quindry, Emily G Zehner, Justin McCroskey, Matthew Ferguson, Tony Ward, Charles Dumke, John C Quindry

Abstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Application of a Novel Collection of Exhaled Breath Condensate to Exercise Settings.International journal of environmental research and public health · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bridget PetersSchool of Kinesiology, Auburn University, Auburn, Alabama (Dr Peters, Dr Ballmann, Ms Zehner, Mr McCroskey); Department of Health and Human Performance (Ms Quindry, Dr Dumke, Dr Quindry); Center for Environmental Health Sciences (Mr Ferguson); School of Public and Community Health Sciences (Dr Ward), University of Montana, Missoula, Montana.
Christopher Ballmann
Tiffany Quindry
Emily G Zehner
Justin McCroskey
Matthew Ferguson
Tony Ward
Charles Dumke
John C Quindry

Funding

THE ROLE OF PULMONARY SUBPOPULATIONS AND TH2 IMMUNITY IN BALB/C SILICOSIS MODELP20RR017670 · NCRR · UNIVERSITY OF MONTANA · PI ROBERTS, KEVAN · 2002 to 2011
$22.0M
Molecular Histology and Fluorescent ImagingP30GM103338 · NIGMS · UNIVERSITY OF MONTANA · PI ROBERTS, KEVAN · 2013 to 2017
$5.6M
NCRR NIH HHS P20 RR017670NIGMS NIH HHS P30 GM103338
6 · The paper itself

Abstract

objectivesThe current laboratory study quantified blood oxidative stress to woodsmoke exposure.

methodsParticipants inhaled woodsmoke during three randomized crossover exercise trials (Clean Air [0 μg/m], Low Exposure [250 μg/m], and High Exposure [500 μg/m], Woodsmoke [particulate matter less than 2.5 μm, PM2.5]). Trolox equivalent antioxidant capacity (TEAC), uric acid (UA), 8-isoprostanes (8-ISO), lipid hydroperoxides (LOOH), protein carbonyls (PC), nitrotyrosine (3-NT), 8-isoprostane, and myeloperoxidase (MPO) were quantified in Pre, immediately Post, and 1- (1Hr) hour post blood samples.

resultsUA decreased following Low Exposure, while plasma TEAC levels increased Post and 1Hr. LOOH levels decreased 1Hr Post (High Exposure), while 8-Iso increased following both smoke trials. PC and MPO were unchanged following all trials, while 3-NT increased over Clean Air.

conclusionBlood oxidative stress occurred largely independent of PM2.5 concentrations. Future studies should employ longer duration smoke and exercise combined with physiologic parameters.

Indexed as

Oxidative StressPhysical ExertionAdultAntioxidantsCross-Over StudiesDinoprostExercise TestHumansInhalation ExposureIsoprostanesLipid PeroxidesParticulate MatterPeroxidaseProtein CarbonylationRandom AllocationSmoke3-nitrotyrosine8-epi-prostaglandin F2alphaAntioxidantsDinoprostIsoprostanesLipid PeroxidesParticulate MatterPeroxidaseSmokeTyrosineUric Acid

Identifiers

PMID30188494
PMCPMC6289726

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.