ArticleeLife2018
Receptive field center-surround interactions mediate context-dependent spatial contrast encoding in the retina.
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Atypical Use of Visuospatial Context in Psychotic Psychopathology: A Meta-analysis.Schizophrenia bulletin · 2025Pooled it
- A standard model for the vertebrate retina.Vision research · 2026Article
- Filter, Detector, Predictor: The expanding repertoire of retinal computation in vertebrates.Vision research · 2026Review
- Spatially local inhibition and synaptic plasticity together enable dynamic, context-dependent integration of parallel sensory pathways.Cell reports · 2026Article
- Spatial Adaptation of Primate Retinal Ganglion Cells Between Artificial and Natural Stimuli.eNeuro · 2026Article
- Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies.PLoS computational biology · 2026Article
- Decoding the roles of bipolar, amacrine, and horizontal cells.Handbook of clinical neurology · 2026Review
- Spatially-local inhibition and synaptic plasticity together enable dynamic, context-dependent integration of parallel sensory pathways.bioRxiv : the preprint server for biology · 2025Article
- Article
- Compartmentalized pooling generates orientation selectivity in wide-field amacrine cells.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Impact of Glaucomatous Ganglion Cell Damage on Central Visual Function.Annual review of vision science · 2024Review
- Dynamic Nonlinear Spatial Integrations on Encoding Contrasting Stimuli of Tectal Neurons.Animals : an open access journal from MDPI · 2024Article
- Heterogeneous presynaptic receptive fields contribute to directional tuning in starburst amacrine cells.eLife · 2023Article
- Heterogeneous presynaptic receptive fields contribute to directional tuning in starburst amacrine cells.bioRxiv : the preprint server for biology · 2023Article
- Generalizing biological surround suppression based on center surround similarity via deep neural network models.PLoS computational biology · 2023Article
- Pattern forming mechanisms of color vision.Network neuroscience (Cambridge, Mass.) · 2023Article
- Systematic reduction of the dimensionality of natural scenes allows accurate predictions of retinal ganglion cell spike outputs.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Center-surround interactions underlie bipolar cell motion sensitivity in the mouse retina.Nature communications · 2022Article
- Classical center-surround receptive fields facilitate novel object detection in retinal bipolar cells.Nature communications · 2022Article
- Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
Antagonistic receptive field surrounds are a near-universal property of early sensory processing. A key assumption in many models for retinal ganglion cell encoding is that receptive field surrounds are added only to the fully formed center signal. But anatomical and functional observations indicate that surrounds are added before the summation of signals across receptive field subunits that creates the center. Here, we show that this receptive field architecture has an important consequence for spatial contrast encoding in the macaque monkey retina: the surround can control sensitivity to fine spatial structure by changing the way the center integrates visual information over space. The impact of the surround is particularly prominent when center and surround signals are correlated, as they are in natural stimuli. This effect of the surround differs substantially from classic center-surround models and raises the possibility that the surround plays unappreciated roles in shaping ganglion cell sensitivity to natural inputs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.