Evidence map›Paper›PMID 30188137›Full record

ArticleOrganic letters2018

Asmic: An Exceptional Building Block for Isocyanide Alkylations.

Embarek Alwedi, J Armando Lujan-Montelongo, Bhaskar R Pitta, Allen Chao, Rodrigo Cortés-Mejía, Jorge M Del Campo, Fraser F Fleming

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organic letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Embarek AlwediDepartment of Chemistry , Drexel University , 32 South 32nd Street , Philadelphia , Pennsylvania 19104 , United States.
J Armando Lujan-MontelongoDepartment of Chemistry , Drexel University , 32 South 32nd Street , Philadelphia , Pennsylvania 19104 , United States.
Bhaskar R PittaDepartment of Chemistry , Drexel University , 32 South 32nd Street , Philadelphia , Pennsylvania 19104 , United States.
Allen ChaoDepartment of Chemistry , Drexel University , 32 South 32nd Street , Philadelphia , Pennsylvania 19104 , United States.
Rodrigo Cortés-MejíaDepartment of Chemistry , Drexel University , 32 South 32nd Street , Philadelphia , Pennsylvania 19104 , United States.
Jorge M Del CampoDepartment of Chemistry , Drexel University , 32 South 32nd Street , Philadelphia , Pennsylvania 19104 , United States.ORCID 0000-0002-4195-3487
Fraser F FlemingDepartment of Chemistry , Drexel University , 32 South 32nd Street , Philadelphia , Pennsylvania 19104 , United States.ORCID 0000-0002-9637-0246

Funding

Nitrile-Containing Decalins in MedicineR15AI051352 · NIAID · DUQUESNE UNIVERSITY · PI BEAVER, BRUCE · 2002 to 2012
$1.1M
NIAID NIH HHS R15 AI051352
6 · The paper itself

Abstract

Asmic addresses the long-standing challenge of alkylating isocyanides, providing access to isocyanides with diverse substitution patterns. The o-anisylsulfanyl group serves a critical dual role by facilitating deprotonation-alkylation and providing a latent nucleophilic site through an unusual arylsulfanyl-lithium exchange.

Indexed as

AlkanesAlkylationCyanidesLithiumMolecular StructureOrganometallic CompoundsSulfhydryl CompoundsAlkanesCyanidesLithiumOrganometallic CompoundsSulfhydryl Compounds

Identifiers

PMID30188137
PMCPMC6172042

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.