ArticleMagnetic resonance in medicine2019
Improved sensitivity and temporal resolution in perfusion FMRI using velocity selective inversion ASL.
Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed.
- A straightforward approach for 3D single-shot arterial spin labeling-based brain perfusion imaging: Preventing artifacts due to signal fluctuations.Magnetic resonance in medicine · 2025Article
- Evaluating cerebrovascular reactivity measured by velocity selective inversion arterial spin labeling with different post-labeling delays: The effect of fast flow.Magnetic resonance in medicine · 2024Article
- Direct angiographic comparison of different velocity-selective saturation, inversion, and DANTE labeling modules on cerebral arteries.Magnetic resonance in medicine · 2024Article
- Article
- Evaluation of 3D stack-of-spiral turbo FLASH acquisitions for pseudo-continuous and velocity-selective ASL-derived brain perfusion mapping.Magnetic resonance in medicine · 2023Article
- Test-retest reliability of 3D velocity-selective arterial spin labeling for detecting normal variations of cerebral blood flow.NeuroImage · 2023Article
- Robust dual-module velocity-selective arterial spin labeling (dm-VSASL) with velocity-selective saturation and inversion.Magnetic resonance in medicine · 2023Article
- Velocity-selective excitation: Principles and applications.NMR in biomedicine · 2023Review
- Recent Technical Developments in ASL: A Review of the State of the Art.Magnetic resonance in medicine · 2022Review
- Velocity-selective arterial spin labeling perfusion MRI: A review of the state of the art and recommendations for clinical implementation.Magnetic resonance in medicine · 2022Review
- TMagnetic resonance in medicine · 2022Article
- Magnetic resonance angiography and perfusion mapping by arterial spin labeling using Fourier transform-based velocity-selective pulse trains: Examination on a commercial perfusion phantom.Magnetic resonance in medicine · 2021Article
- Multi-organ comparison of flow-based arterial spin labeling techniques: Spatially non-selective labeling for cerebral and renal perfusion imaging.Magnetic resonance in medicine · 2021Article
- Ensuring both velocity and spatial responses robust toMagnetic resonance in medicine · 2021Article
- Comparison of velocity-selective arterial spin labeling schemes.Magnetic resonance in medicine · 2021Article
- Improved velocity-selective-inversion arterial spin labeling for cerebral blood flow mapping with 3D acquisition.Magnetic resonance in medicine · 2020Article
- Influence of the cardiac cycle on velocity selective and acceleration selective arterial spin labeling.Magnetic resonance in medicine · 2020Article
- Image registration in dynamic renal MRI-current status and prospects.Magma (New York, N.Y.) · 2020Review
- In vivo magnetic resonance imaging and spectroscopy. Technological advances and opportunities for applications continue to abound.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2019Review
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Abstract
purposeThis work aims to investigate the utility of velocity selective inversion pulses for perfusion weighted functional MRI.
methodsTracer kinetic properties of velocity selective inversion (VSI) pulses as an input function for an arterial spin labeling (ASL) experiment were characterized in a group of healthy participants. Numerical simulations were conducted to search for a robust set of timing parameters for FMRI time series acquisition with maximal signal to noise ratio efficiency. The performance of three VSI pulse sequences with different timing parameters was compared with a pseudocontinuous ASL sequence in a simple FMRI experiment conducted on healthy participants.
resultsThe fit to the tracer kinetic model yielded arterial CBV of 1.24% ± 0.52% and 0.45 ± 0.11% and perfusion rates of 60.8 ± 32.3 and 34.4 ± 5.4 mL/min/100 g for gray and white matter, respectively. Bolus arrival times were estimated as 75.7 ± 21 ms and 349 ± 78 ms for gray and white matter, respectively. The FMRI experiments showed that VSI pulses yield comparable sensitivity to PCASL with similar timing parameters (TR = 4 s). However, VSI pulses could be used at a faster acquisition speed (TR = 3 s) and were more sensitive to neuronal activity than PCASL pulses, as evidenced by the 31% higher Z scores obtained on average in the active regions.
conclusionVSI pulses can be very beneficial for perfusion weighted functional MRI because of their tracer kinetic characteristics, which allow a faster acquisition rate while maintaining an efficient labeling input function.
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