Evidence map›Paper›PMID 30187709›Full record

ArticleYonsei medical journal2018

Bronchiectasis and Recurrent Respiratory Infections with a

Hee Jae Huh, Byung Woo Jhun, Sae Rom Choi, Yae Jean Kim, Sun Ae Yun, Eliel Nham, Taehwan Kong, Chang Seok Ki, Won Jung Koh

Open access · goldAbstract readCase Reports
In one paragraph

Article in Yonsei medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hee Jae Huh *Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Byung Woo Jhun *Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Sae Rom ChoiDivision of Pediatric Infectious Diseases and Immunodeficiency, Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Yae Jean KimDivision of Pediatric Infectious Diseases and Immunodeficiency, Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Sun Ae YunCenter for Clinical Medicine, Samsung Biomedical Research Institute, Samsung Medical Center, Seoul, Korea.
Eliel NhamDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Taehwan KongDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Chang Seok KiGreen Cross Genome, Yongin, Korea. changski.md@gmail.com.ORCID https://orcid.org/0000-0001-7679-8731
Won Jung KohDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. wjkoh@skku.edu.ORCID https://orcid.org/0000-0002-4756-3527
Samsung Medical Center · KRGreen Cross (South Korea) · KR

Funding

Korea Health Industry Development Institute HI15C2778
6 · The paper itself

Abstract

Bronchiectasis is a chronic disease characterized by airway infection and inflammation, leading to permanent dilation of the bronchi. Evaluation of underlying etiology is important in managing young bronchiectasis patients with recurrent infections caused by unusual pathogens. The signal transducer and activator of transcription 1 (STAT1) protein plays a key role in STAT signaling and immune system regulation. Heterozygotes for gain-of-function (GOF) alleles of the

Indexed as

Gain of Function MutationBronchiectasisCandidiasis, Chronic MucocutaneousExome SequencingFemaleHumansMutationPolymorphism, Single NucleotideRepublic of KoreaRespiratory Tract InfectionsSignal TransductionSTAT1 Transcription FactorYoung AdultSTAT1 protein, humanSTAT1 Transcription FactorBronchiectasischronic mucocutaneous candidiasisgain-of-function mutationnontuberculous mycobacteriaSTAT1 transcription factor

Identifiers

PMID30187709
PMCPMC6127433
OpenAlexW2891604844

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.