Evidence map›Paper›PMID 30187663›Full record

ArticlePhysiological reports2018

Voltage effects on muscarinic acetylcholine receptor-mediated contractions of airway smooth muscle.

Iurii Semenov, Robert Brenner

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Molecules (Basel, Switzerland) · 2024
    Article
  3. Antifungal activity and antidiarrheal activityWorld journal of gastroenterology · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Iurii SemenovFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, Virginia.
Robert BrennerDepartment of Cell and Integrative Physiology, University of Texas Health Science Center San Antonio, San Antonio, Texas.
Integrative Health Technologies (United States) · USOld Dominion University · US

Funding

SK channel antagonists as novel bronchodilators for asthmaR21AI113724 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BRENNER, ROBERT · 2014 to 2015
$407k
NIAID NIH HHS AI113724NIAID NIH HHS R21 AI113724
6 · The paper itself

Abstract

Studies have shown that the activity of muscarinic receptors and their affinity to agonists are sensitive to membrane potential. It was reported that in airway smooth muscle (ASM) depolarization evoked by high K

Indexed as

Membrane PotentialsMuscle ContractionAnimalsCalcium ChannelsCells, CulturedMiceMice, Inbred C57BLMyocytes, Smooth MusclePotassiumReceptors, MuscarinicTracheaCalcium ChannelsPotassiumReceptors, MuscarinicAcetylcholine receptorsairway smooth musclecalcium channelscontractionsvoltage

Identifiers

PMID30187663
PMCPMC6125245
OpenAlexW2891969116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.