Evidence map›Paper›PMID 30187246›Full record

ArticleMycopathologia2018

Determination of Azole Resistance and TR

Özge Güngör, Benedita Sampaio-Maia, Antonio Amorim, Ricardo Araujo, Zayre Erturan

Abstract read
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In one paragraph

Article in Mycopathologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Investigation of azole resistance inJournal of medical microbiology · 2026
    Article
  2. First Report of Azole-ResistantJournal of fungi (Basel, Switzerland) · 2023
    Article
  3. Review
  4. Azole-ResistantFrontiers in microbiology · 2020
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Özge GüngörIstanbul Medical Faculty, Department of Medical Microbiology, Istanbul University, 34093, Capa, Istanbul, Turkey. ozgegungor@hotmail.com.ORCID http://orcid.org/0000-0001-5448-9102
Benedita Sampaio-MaiaFaculty of Dental Medicine, University of Porto, Porto, Portugal.
Antonio Amorimi3S, Instituto de Investigação e Inovação em Saúde da Universidade do Porto, Porto, Portugal.
Ricardo Araujoi3S, Instituto de Investigação e Inovação em Saúde da Universidade do Porto, Porto, Portugal.
Zayre ErturanIstanbul Medical Faculty, Department of Medical Microbiology, Istanbul University, 34093, Capa, Istanbul, Turkey.
Istanbul University · TRUniversidade do Porto · PTFlinders University · AU

Funding

Federation of European Microbiological Societies (FEMS) Research Fellowship 2015-0048Research Fund of Istanbul University 47641
6 · The paper itself

Abstract

backgroundAspergillus fumigatus is the species section Fumigati most frequently isolated from the respiratory tract of cystic fibrosis (CF) patients. Recent studies suggest that mutations in the Cyp51 gene, particularly TR OBJECTIVES AND

methodsThe focus of this study was on section Fumigati isolates isolated from the respiratory tract samples of CF patients. More specifically, the goal was to detect A. fumigatus isolates, test their antifungal susceptibility to itraconazole, voriconazole and posaconazole, and finally determine the presence of TR RESULTS AND

conclusionsA set of 31 isolates of Aspergillus section Fumigati were obtained from the sputum samples of 6 CF patients and subsequently identified to species level by microsatellite genotyping. All isolates were determined as A. fumigatus and involved 14 different genotypes. The minimal inhibitory concentrations to the three azoles were determined by the E-test method, and the Cyp51A gene was sequenced. One of the genotypes was found to be resistant to all azoles but no mutations were detected in the Cyp51A gene, especially the TR

Indexed as

Drug Resistance, FungalMutationAdolescentAdultAntifungal AgentsAspergillus fumigatusAzolesChildCystic FibrosisFemaleGenotypeGenotyping TechniquesHumansMaleMicrobial Sensitivity TestsMicrosatellite RepeatsAntifungal AgentsAzolesSterol 14-DemethylaseAspergillus fumigatusAzole resistanceCyp51ACystic fibrosisSection FumigatiTR34/L98H mutations

Identifiers

PMID30187246
OpenAlexW2892347640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.