Evidence map›Paper›PMID 30187211›Full record

ArticleMikrochimica acta2018

A colorimetric assay for acetylcholinesterase activity and inhibitor screening based on the thiocholine-induced inhibition of the oxidative power of MnO

Yuan Sun, Haonan Tan, Yinhuan Li

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. MnOMikrochimica acta · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yuan SunDepartment of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an, 710049, China.
Haonan TanDepartment of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an, 710049, China.
Yinhuan LiDepartment of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an, 710049, China. liyh@mail.xjtu.edu.cn.
Xi'an Jiaotong University · CN

Funding

Fundamental Research Funds for the Central Universities xjj2015121
6 · The paper itself

Abstract

The authors describe a colorimetric method for the determination of the activity of acetylcholinesterase (AChE). Manganese dioxide (MnO

Indexed as

AcetylcholinesteraseBenzidinesCholinesterase InhibitorsColorimetryDrug Evaluation, PreclinicalEnzyme AssaysInhibitory Concentration 50Manganese CompoundsNanostructuresOxidation-ReductionOxidesThiocholine3,3',5,5'-tetramethylbenzidineAcetylcholinesteraseBenzidinesCholinesterase InhibitorsManganese Compoundsmanganese oxideOxidesThiocholine3,3′,5,5′–TetramethylbenzidineAcetylcholinesteraseAcetylcholinesterase activityAcetylthiocholine chlorideColorimetryInhibitor screeningMnO2 nanosheetsNeostigmineOxidation

Identifiers

PMID30187211
OpenAlexW2889649844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.