Evidence map›Paper›PMID 30186857›Full record

ArticleBioMed research international2018

Histogram Analysis of Perfusion Parameters from Dynamic Contrast-Enhanced MR Imaging with Tumor Characteristics and Therapeutic Response in Locally Advanced Rectal Cancer.

Dong Myung Yeo, Soon Nam Oh, Moon Hyung Choi, Sung Hak Lee, Myung Ah Lee, Seung Eun Jung

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. The Role of Radiomics in Rectal Cancer.Journal of gastrointestinal cancer · 2023
    Review
  2. Article
  3. Review
  4. T2-weighted, apparent diffusion coefficient andTechniques in coloproctology · 2021
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dong Myung YeoDepartment of Radiology, Daejeon St. Mary's Hospital, The Catholic University of Korea, Republic of Korea.ORCID 0000-0002-1362-1362
Soon Nam OhDepartments of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea, Republic of Korea.ORCID 0000-0003-2373-7024
Moon Hyung ChoiDepartments of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea, Republic of Korea.
Sung Hak LeeHospital Pathology, Seoul St. Mary's Hospital, The Catholic University of Korea, Republic of Korea.
Myung Ah LeeDivision of Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Republic of Korea.
Seung Eun JungDepartments of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea, Republic of Korea.ORCID 0000-0003-0674-5444
The Catholic University of Korea Seoul St. Mary's Hospital · KRThe Catholic University of Korea Daejeon St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore the role of histogram analysis of perfusion parameters from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) based on entire tumor volume in discriminating tumor characteristics and predicting therapeutic response in rectal cancer. MATERIALS AND

methodsThirty-seven DCE-MRIs of locally advanced rectal cancer patients who received chemoradiation therapy (CRT) before surgery were analyzed by pharmacokinetic model for quantification and histogram analysis of perfusion parameters. The results were correlated with tumor characteristics including EGFR expression, KRAS mutation, and CRT response based on the pathologic tumor regression grade (TRG).

resultsThe area under the contrast agent concentration-time curve (AUC) skewness was significantly lower in patients with node metastasis. The v

conclusionThese preliminary results suggest that a larger proportion of higher AUC skewness was present in LN metastasis group and a higher v

Indexed as

Contrast MediaAdultAgedAged, 80 and overChemoradiotherapyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPrognosisProto-Oncogene Proteins p21(ras)Rectal NeoplasmsRetrospective StudiesROC CurveStatistics, NonparametricContrast MediaKRAS protein, humanProto-Oncogene Proteins p21(ras)

Identifiers

PMID30186857
PMCPMC6110013
OpenAlexW2886057230

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.