Evidence map›Paper›PMID 30186662›Full record

ReviewSurgical neurology international2018

A review of the disagreements in the prevalence and treatment of the tethered cord syndromes with chiari-1 malformations.

Nancy E Epstein

Open access · hybridAbstract readReview
In one paragraph

Review in Surgical neurology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. The management of Chiari malformation type 1 and syringomyelia in children: a review of the literature.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Nancy E EpsteinProfessor of Clinical Neurosurgery, School of Medicine, State University of N.Y. at Stony Brook, Mineola, New York, USA.
Stony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe tethered cord syndrome (TCS) accompanying Chiari-1 (CM-1) malformations and the occult tethered cord syndrome (OTCS) syndrome accompanying the low lying cerebellar tonsil (LLCT) syndrome may be treated with sectioning of the filum terminale (SFT).

methodsUtilizing PubMed, we reviewed the neurosurgical literature to determine how frequently spinal neurosurgeons diagnosed the TCS (e.g., conus terminating below the normal L1-L2 disc level) on lumbar magnetic resonance (MR) studies in patients with CM-1 malformations [e.g. tonsils >5-12 mm below the foramen magnum (FM) warranting SFT]. In addition, we assessed how frequently spinal neurosurgeons encountered the OTCS (e.g., conus normally located at L1-L2 on MR) accompanying the LLCT (e.g., tonsils herniated <5 mm below the FM) also requiring SFT.

resultsAccording to the neurosurgical literature, the incidence of TCS accompanying CM-1 requiring SFT ranged from 2.2% to < 6%, and up to 14%. Few studies additionally highly correlated the OCTS accompanying the LLCT syndrome warranting SFT.

conclusionsGiven the differences in the literature, more studies are needed to assess the risks (complications) vs. benefits (improved neurological outcomes) of SFT surgery for TCS with CM-1 and SFT for OCTS with LLCT.

Indexed as

Chiari-1 malformationsdefinitionsindicationslow lying cerebellar tonsil syndromeoccult tethered cord syndromeprevalencesection of filum terminaletethered cord syndrome

Identifiers

PMID30186662
PMCPMC6108168
OpenAlexW2885578254

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.