Evidence map›Paper›PMID 30186660›Full record

ReviewPublic health reviews2018

Screening and treatment of hypertension in older adults: less is more?

Daniela Anker, Brigitte Santos-Eggimann, Valérie Santschi, Cinzia Del Giovane, Christina Wolfson, Sven Streit, Nicolas Rodondi, Arnaud Chiolero

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Public health reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Credibility of self-reported health parameters in elderly population.Primary health care research & development · 2020
    Article
  19. Blood pressure in relation to frailty in older adults: A population-based study.Journal of clinical hypertension (Greenwich, Conn.) · 2019
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Daniela Anker1Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.ORCID 0000-0002-0607-0283
Brigitte Santos-Eggimann2Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Lausanne, Switzerland.
Valérie SantschiLa Source, School of Nursing Sciences, University of Applied Sciences and Arts Western Switzerland, Lausanne, Switzerland.
Cinzia Del Giovane1Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Christina Wolfson4Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada.
Sven Streit1Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Nicolas Rodondi1Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Arnaud Chiolero1Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
University of Bern · CHHES-SO University of Applied Sciences and Arts Western Switzerland · CHInstitute of Social and Preventive Medicine · CHMcGill University Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Screening and treatment of hypertension is a cornerstone of cardiovascular disease (CVD) prevention. Hypertension causes a large proportion of cases of stroke, coronary heart disease, heart failure, and associated disability and is highly prevalent especially among older adults. On the one hand, there is robust evidence that screening and treatment of hypertension prevents CVD and decreases mortality in the middle-aged population. On the other hand, among older adults, observational studies have shown either positive, negative, or no correlation between blood pressure (BP) and cardiovascular outcomes. Furthermore, there is a lack of high quality evidence for a favorable harm-benefit balance of antihypertensive treatment among older adults, especially among the oldest-old (i.e., above the age of 80 years), because very few trials have been conducted in this population. The optimal target BP may be higher among older treated hypertensive patients than among middle-aged. In addition, among frail or multimorbid older individuals, a relatively low BP may be associated with worse outcomes, and antihypertensive treatment may cause more harm than benefit. To guide hypertension screening and treatment recommendations among older patients, additional studies are needed to determine the most efficient screening strategies, to evaluate the effect of lowering BP on CVD risk and on mortality, to determine the optimal target BP, and to better understand the relationship between BP, frailty, multimorbidity, and health outcomes.

Indexed as

FrailtyHypertensionOlder adultsScreening

Identifiers

PMID30186660
PMCPMC6120092
OpenAlexW2884485392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.