Evidence map›Paper›PMID 30186459›Full record

ReviewExperimental and therapeutic medicine2018

Applications and development of permeability imaging in ischemic stroke.

Hui Chen, Guangming Zhu, Nan Liu, Ying Li, Yonghong Xia

Abstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hui ChenDepartment of Neurology, Military General Hospital of Beijing PLA, Beijing 100700, P.R. China.
Guangming ZhuDepartment of Neurology, Military General Hospital of Beijing PLA, Beijing 100700, P.R. China.
Nan LiuDepartment of Neurology, Military General Hospital of Beijing PLA, Beijing 100700, P.R. China.
Ying LiDepartment of Neurology, Military General Hospital of Beijing PLA, Beijing 100700, P.R. China.
Yonghong XiaDepartment of Critical Care Medicine, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain permeability imaging techniques are specific for the assessment of blood-brain barrier integrity. The present review article primarily focuses on the application of permeability imaging in cases of ischemic stroke. The permeability maps may be used to predict future hemorrhagic transformation in patients following acute ischemic stroke, that have been treated with tissue plasminogen activator (tPA) or recanalization therapy. The permeability imaging would help make the clinical decision to administer tPA following acute ischemic stroke or not, which is not only due to the current 3-4.5 h time window. Additionally, permeability imaging may also be used to evaluate the collateral circulation in the perfusion and permeability of the ischemic area of the brain.

Indexed as

acute ischemic strokeblood brain barrier permeabilityhemorrhagic transformationintracranial collateral circulation

Identifiers

PMID30186459
PMCPMC6122297

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.