Evidence map›Paper›PMID 30186457›Full record

ReviewExperimental and therapeutic medicine2018

Novel treatment strategies for patients with HER2-positive breast cancer who do not benefit from current targeted therapy drugs.

Nan Jiang, Jing-Jing Lin, Jun Wang, Bei-Ning Zhang, Ao Li, Zheng-Yang Chen, Song Guo, Bin-Bin Li, Yu-Zhong Duan, Ru-Yi Yan and 5 more

Open access · diamondAbstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Nan JiangDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
Jing-Jing LinDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
Jun WangDepartment of Hepatology, 302 Teaching Hospital of Peking University Health Science Center, Beijing 100101, P.R. China.
Bei-Ning ZhangDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
Ao LiDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
Zheng-Yang ChenDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
Song GuoDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
Bin-Bin LiDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
Yu-Zhong DuanDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
Ru-Yi YanDepartment of General Surgery, PLA 306 Clinical Hospital of Anhui Medical University, Beijing 230000, P.R. China.
Hong-Feng YanDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
Xiao-Yan FuDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
Jin-Lian ZhouDepartment of Pathology, 306 Hospital of PLA, Beijing 100101, P.R. China.
He-Ming YangDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
Yan CuiDepartment of General Surgery, 306 Hospital of PLA, Beijing 100101, P.R. China.
PLA 306 Hospital · CNAnhui Medical University · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human epidermal growth factor receptor-2 positive breast cancer (HER2

Indexed as

drug resistanceHER2 target therapynatural anti-cancer substancesneratinibtargeted delivery drugstrastuzumab

Identifiers

PMID30186457
PMCPMC6122384
OpenAlexW2883757758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.