Evidence map›Paper›PMID 30186438›Full record

ArticleExperimental and therapeutic medicine2018

Improved heart failure by Rhein lysinate is associated with p38MAPK pathway.

Wei Wang, Xin Meng, Jing Wang, Yong Li

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Phytochemical Rhein Mediates MFrontiers in nutrition · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Wei WangInternal Medicine-Cardiovascular Department, Tengzhou Central People's Hospital Affiliated to Jining Medical University, Zaozhuang, Shandong 277500, P.R. China.
Xin MengInternal Medicine-Cardiovascular Department, Tengzhou Central People's Hospital Affiliated to Jining Medical University, Zaozhuang, Shandong 277500, P.R. China.
Jing WangInternal Medicine-Cardiovascular Department, Tengzhou Central People's Hospital Affiliated to Jining Medical University, Zaozhuang, Shandong 277500, P.R. China.
Yong LiInternal Medicine-Cardiovascular Department, Tengzhou Central People's Hospital Affiliated to Jining Medical University, Zaozhuang, Shandong 277500, P.R. China.
Jining Medical University · CNAffiliated Hospital of Jining Medical University · CNTengzhou Central People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to explore the role of Rhein lysinate (RHL) in neonatal rat ventricular myocytes (NRVMs) and congestive heart failure induced by co-arctation of the abdominal aorta. Male Sprague-Dawley rats were divided into 3 groups randomly: co-arctation of abdominal aorta group (A group, n=10), sham operation group (SH group, n=10) and RHL treatment rats (A+RHL group, n=10). To establish an

Indexed as

apoptosisheart failurep38MAPKRhein lysinate

Identifiers

PMID30186438
PMCPMC6122205
OpenAlexW2870429789

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.